Plasmid Content of a Clinically Relevant Klebsiella pneumoniae Clone from the Czech Republic Producing CTX-M-15 and QnrB1

被引：40

作者：

Dolejska, Monika ^{[1
,2
]}

Villa, Laura ^{[3
]}

Dobiasova, Hana ^{[1
]}

Fortini, Daniela ^{[3
]}

Feudi, Claudia ^{[3
]}

Carattoli, Alessandra ^{[3
]}

机构：

[1] Univ Vet & Pharmaceut Sci Brno, Fac Vet Hyg & Ecol, Dept Biol & Wildlife Dis, Brno, Czech Republic

[2] Univ Vet & Pharmaceut Sci Brno, CEITEC VFU, Brno, Czech Republic

[3] Ist Super Sanita, Dept Infect Parasit & Immune Mediated Dis, I-00161 Rome, Italy

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2013年 / 57卷 / 02期

关键词：

ESCHERICHIA-COLI; NUCLEOTIDE-SEQUENCE; VIRULENCE;

D O I：

10.1128/AAC.01886-12

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The entire plasmid content of a multidrug-resistant, CTX-M-15-producing Klebsiella pneumoniae ST416 clone was investigated. Two FII kappa plasmids, pKDO1 (127 kb) and pKPN-CZ (207 kb), were identified and found to carry a formidable set of genes conferring resistance to toxic compounds, metals, and antimicrobial drugs and exhibiting novel features putatively associated with adaptation and fitness of the bacterium in the human host.

引用

页码：1073 / 1076

页数：4

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