A Microfabricated Rotary Pump

被引：172

作者：

Chou, Hou-Pu ^{[1
]}

Unger, Marc A. ^{[2
]}

Quake, Stephen R. ^{[2
]}

机构：

[1] CALTECH, Dept Elect Engn, Pasadena, CA 91125 USA

[2] CALTECH, Dept Appl Phys, Pasadena, CA 91125 USA

来源：

BIOMEDICAL MICRODEVICES | 2001年 / 3卷 / 04期

关键词：

microfluidics; microelectromechanical systems; soft lithography; lab on a chip; diffusion;

D O I：

10.1023/A:1012412916446

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Because microfluidic devices operate at low Reynolds number, many fluidic operations are limited by diffusion. We have developed a microfabricated rotary pump and demonstrated that active mixing can be used to overcome the slow diffusion process in two applications. First, we showed that mixing of reagents could be efficiently accomplished for objects of a wide range of diffusion constants. Second, we showed how reaction kinetics of a surface-binding assay can be enhanced by nearly two orders of magnitude.

引用

页码：323 / 330

页数：8

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