Molecular Imaging of Inflammation: Current Status

被引：39

作者：

Hammoud, Dima A. ^{[1
]}

机构：

[1] NIH, Ctr Infect Dis Imaging Radiol & Imaging Sci, Bldg 10, Bethesda, MD 20892 USA

来源：

JOURNAL OF NUCLEAR MEDICINE | 2016年 / 57卷 / 08期

关键词：

inflammation; molecular imaging; PET; MRI; iron oxide nanoparticles; POSITRON-EMISSION-TOMOGRAPHY; IRON-OXIDE; DISEASE-ACTIVITY; FDG PET/CT; ATHEROSCLEROSIS; NANOPARTICLES; MRI; RADIOLIGANDS; MACROPHAGES; DIAGNOSIS;

D O I：

10.2967/jnumed.115.161182

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

The ability to image inflammation in vivo can improve our understanding of the pathophysiology underlying various disease etiologies, including cancer, atherosclerosis, and neurodegeneration. A great wealth of preclinical and translational research has been and is currently being developed to decipher the involvement of the immune system in disease pathophysiology, quantify the course of a disease, and visualize the potential detrimental effects of excessive inflammation. Down the road, the ultimate goal is to have clinical noninvasive in vivo imaging biomarkers of inflammation that will help diagnose disease, establish prognosis, and gauge response to preventative and therapeutic strategies.

引用

页码：1161 / 1165

页数：5

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