Catalyst-mediated yet catalyst-free hydrogels formed by interfacial chemical activation

被引：30
作者：
Byun, Eunkyoung [1 ]
Ryu, Ji Hyun [2 ]
Lee, Haeshin [1 ,2 ]
机构：
[1] Korea Adv Inst Sci & Technol KAIST, Dept Chem, KAIST Inst NanoCentury CNiT, Taejon 305701, South Korea
[2] Korea Adv Inst Sci & Technol KAIST, Grad Sch Nanosci & Technol, Taejon 305701, South Korea
来源：
CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 22期
基金：
新加坡国家研究基金会;
关键词：
DRUG-DELIVERY; CHITOSAN; HEMATIN; CHEMISTRY;
D O I：
10.1039/c3cc49043b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We introduce an entirely new method for forming hydrogels, wherein the formation is triggered by a catalyst, but the resulting hydrogels are catalyst-free. We unexpectedly found that a sufficient amount of crosslinkable catecholquinone/semiquinone free radicals is generated by the physical contact between catechol-containing polymers and surface-immobilized catalysts.
引用
收藏
页码：2869 / 2872
页数：4
相关论文
共 38 条
[1]   Hematin-catalyzed polymerization of phenol compounds [J].
Akkara, JA ;
Wang, JZ ;
Yang, DP ;
Gonsalves, KE .
MACROMOLECULES, 2000, 33 (07) :2377-2382
[2]   Oxidation of 3,4-Dihydroxyphenylacetaldehyde, a Toxic Dopaminergic Metabolite, to a Semiquinone Radical and an ortho-Quinone [J].
Anderson, David G. ;
Mariappan, S. V. Santhana ;
Buettner, Garry R. ;
Doorn, Jonathan A. .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (30) :26978-26986
[3]   Structure and interactions in covalently and ionically crosslinked chitosan hydrogels for biomedical applications [J].
Berger, J ;
Reist, M ;
Mayer, JM ;
Felt, O ;
Peppas, NA ;
Gurny, R .
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2004, 57 (01) :19-34
[4]   Enzyme-catalyzed gel formation of gelatin and chitosan: potential for in situ applications [J].
Chen, TH ;
Embree, HD ;
Brown, EM ;
Taylor, MM ;
Payne, GF .
BIOMATERIALS, 2003, 24 (17) :2831-2841
[5]   Versatile Biofunctionalization of Polypeptide-Based Thermosensitive Hydrogels via Click Chemistry [J].
Cheng, Yilong ;
He, Chaoliang ;
Xiao, Chunsheng ;
Ding, Jianxun ;
Cui, Haitao ;
Zhuang, Xiuli ;
Chen, Xuesi .
BIOMACROMOLECULES, 2013, 14 (02) :468-475
[6]   Chemical and Structural Diversity in Eumelanins: Unexplored Bio-Optoelectronic Materials [J].
d'Ischia, Marco ;
Napolitano, Alessandra ;
Pezzella, Alessandro ;
Meredith, Paul ;
Sarna, Tadeusz .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (22) :3914-3921
[7]   Hydrogels for tissue engineering: scaffold design variables and applications [J].
Drury, JL ;
Mooney, DJ .
BIOMATERIALS, 2003, 24 (24) :4337-4351
[8]  
FITCH CD, 1983, BLOOD, V62, P1165
[9]   Hydrogels in drug delivery: Progress and challenges [J].
Hoare, Todd R. ;
Kohane, Daniel S. .
POLYMER, 2008, 49 (08) :1993-2007
[10]   Hydrogels for biomedical applications [J].
Hoffman, Allan S. .
ADVANCED DRUG DELIVERY REVIEWS, 2012, 64 :18-23
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