Evaluation of the management of pregnancies and infants at risk for congenital syphilis: La Reunion, 2008 to 2014

被引:7
作者
de Preville, M. Le Chevalier [1 ]
Alessandri, J-L [1 ]
Traversier, N. [2 ]
Cuillier, F. [3 ]
Robin, S. [4 ]
Ramful, D. [1 ]
机构
[1] CHU Reunion, Felix Guyon Hosp, Neonatal & Pediat Intens Care Unit, St Denis 97405, Reunion, France
[2] CHU Reunion, Felix Guyon Hosp, Microbiol Virol Lab, St Denis, Reunion, France
[3] CHU Reunion, Felix Guyon Hosp, Dept Obstet & Gynecol, St Denis, Reunion, France
[4] CHU Reunion, Felix Guyon Hosp, Dept Pediat, St Denis, Reunion, France
关键词
UNITED-STATES; BENZATHINE; PENICILLIN; LONDON;
D O I
10.1038/jp.2016.158
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
OBJECTIVE: To evaluate the maternal-fetal management and follow-up of infants at risk for congenital syphilis. STUDY DESIGN: Monocentric retrospective cohort study at the Felix Guyon Hospital, Saint-Denis, La Reunion between January 2008 and December 2014. Management of 38 pregnancies (35 women, 39 fetuses) with a positive syphilis serology was evaluated according to the Centers for Diseaise Control and Prevention (CDC) guidelines. RESULTS; A total of 68% (n = 26) of pregnancies were screened before 16 weeks of gestation, and 26% (n = 10) had appropriate treatment. Adverse outcomes were noted in 45% of pregnancies. Neonatal serology Was not performed in 7 live-born neonates (19%) and 33 infants were classifiable according to the four CDC scenarios. In the- infant, adequate complementary evaluation and appropriate treatment were noted in 42% (n=13) and 55% 17) of cases, respectively: Rate of infant follow-up was 76% (n=16). No treatment failure was observed in infants. CONCLUSION: Reinforcement of public health policies and a better sensitization, training and collaboration among perinatal caregivers are warranted given the gaps revealed in our study.
引用
收藏
页码:116 / 121
页数:6
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