Selective inhibition of K-Ras G12C through allosteric control of GTP affinity and effector interactions

被引：0
|
作者：
Ostrem, Jonathan M. [1 ]
Peters, Ulf [1 ]
Sos, Martin L. [1 ]
Wells, James A. [2 ]
Shokat, Kevan M. [1 ]
机构：
[1] Univ Calif San Francisco, Howard Hughes Med Inst, San Francisco, CA USA
[2] Univ Calif San Francisco, San Francisco, CA 94143 USA
来源：
MOLECULAR CANCER THERAPEUTICS | 2013年 / 12卷 / 11期
关键词：
D O I：
10.1158/1535-7163.TARG-13-PL04-03
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
PL04-03
引用
收藏
页数：1
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