A new triterpene from Astilbe chinensis

被引:2
作者
Xu, Ying Qian [1 ,2 ]
Pang, Song [2 ]
Hu, Jun Yi [2 ]
Duan, Hong Quan [1 ]
机构
[1] Tianjin Med Univ, Tianjin Key Lab Technol Enabling Dev Clin Therape, Sch Pharmaceut Sci, Res Ctr Basic Med Sci, Tianjin 300070, Peoples R China
[2] Univ Sci & Technol Liaoning, Sch Chem Engn, Ctr Separat Technol, Liaoning 114051, Peoples R China
关键词
Astilbe chinensis; triterpene; cytotoxic activity;
D O I
10.1007/s10600-013-0578-0
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
A new triterpene, 3 beta,19 alpha-dihydroxy-6 beta-acetoxy-ursane (1), was isolated from the rhizomes of Astilbe chinensis. Its structure was elucidated on the basis of 1D and 2D NMR analyses and HR-MS experiments. The isolated compound exhibited cytotoxic activities against HeLa and L929 cell lines.
引用
收藏
页码:268 / 270
页数:3
相关论文
共 7 条
[1]  
Chen Hao, 2004, Zhongguo Zhongyao Zazhi, V29, P652
[2]  
Chen P, 1996, Zhongguo Zhong Yao Za Zhi, V21, P302
[3]  
Hu JY, 2006, CHINESE CHEM LETT, V17, P628
[4]   Triterpenes from Astilbe chinensis [J].
Hu, Jun-Yi ;
Yao, Zhi ;
Xu, Ying-Qian ;
Takaishi, Yoshihisa ;
Duan, Hong-Quan .
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2009, 11 (03) :236-242
[5]  
Jiang Su New Medical College, 1977, DICT CHIN MAT MED
[6]   Cytotoxic pentacyclic triterpenoids from the rhizome of Astilbe chinensis [J].
Sun, HX ;
Zhang, JX ;
Ye, YP ;
Pan, YJ ;
Shen, YA .
HELVETICA CHIMICA ACTA, 2003, 86 (07) :2414-2423
[7]  
Zhang J. T., 1998, MODERN PHARM EXPT ME