Formula to help select rational antimicrobial therapy (FRAT): its application to community- and hospital-acquired urinary tract infections

被引:22
作者
Blondeau, JM
Tillotson, GS
机构
[1] St Pauls Hosp Grey Nuns, Saskatoon, SK, Canada
[2] Univ Saskatchewan, Saskatoon, SK, Canada
[3] Bayer Corp, W Haven, CT USA
关键词
formula; antimicrobial therapy; antimicrobial resistance;
D O I
10.1016/S0924-8579(98)00107-1
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The selection of antimicrobial agents is guided by the use of formularies which often constrain prescribing options. There are several factors which influence the inclusion of specific agents. Two of the most important factors are microbial etiology of a disease and the incidence of antibiotic resistance. Various surveillance programs have highlighted the regional differences in antimicrobial susceptibility/resistance among various pathogens. This simple formula enables individual physicians, pharmacy and therapeutic committees and managed care formulary managers to harness local etiology and susceptibility information. In this paper the formula is applied to community- and hospital-acquired urinary tract infections. (C) 1999 Elsevier Science B.V. and International Society of Chemotherapy. All rights reserved.
引用
收藏
页码:145 / 150
页数:6
相关论文
共 10 条
[1]   Antimicrobial resistance in isolates from inpatients and outpatients in the united states: Increasing importance of the intensive care unit [J].
Archibald, L ;
Phillips, L ;
Monnet, D ;
McGowan, JE ;
Tenover, F ;
Gaynes, R .
CLINICAL INFECTIOUS DISEASES, 1997, 24 (02) :211-215
[2]   Canadian multicenter susceptibility study, with a focus on cephalosporins, from 15 Canadian medical centers [J].
Blondeau, JM ;
Yaschuk, Y ;
Smith, JA ;
Noble, MA ;
Kibsey, P ;
Horsman, GB ;
Hoban, DJ ;
Colby, WD ;
Jessamine, P ;
Simor, AE ;
Low, DE ;
Bourgault, AM ;
Laverdiere, M ;
Kuhn, M ;
MacDonald, S ;
Brown, H .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1997, 41 (12) :2773-2775
[3]   Canadian ciprofloxacin susceptibility study: Comparative study from 15 medical centers [J].
Blondeau, JM ;
Yaschuk, Y .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1996, 40 (07) :1729-1732
[4]  
BLONDEAU JM, 1997, CHEST, V112, P805
[5]  
Davey P G, 1992, Pharmacoeconomics, V1, P409
[6]   Antibiotic resistance among clinical isolates of Haemophilus influenzae in the United States in 1994 and 1995 and detection of beta-lactamase-positive strains resistant to amoxicillin-clavulanate: Results of a national multicenter surveillance study [J].
Doern, GV ;
Brueggemann, AB ;
Pierce, G ;
Holley, HP ;
Rauch, A .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1997, 41 (02) :292-297
[7]   Antimicrobial resistance of Streptococcus pneumoniae recovered from outpatients in the United States during the winter months of 1994 to 1995: Results of a 30-center national surveillance study [J].
Doern, GV ;
Brueggemann, A ;
Holley, HP ;
Rauch, AM .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1996, 40 (05) :1208-1213
[8]  
Johnson C.C., 1996, ANTIBIOTIC LAB MED, V4th, P813
[9]   MAJOR TRENDS IN THE MICROBIAL ETIOLOGY OF NOSOCOMIAL INFECTION [J].
SCHABERG, DR ;
CULVER, DH ;
GAYNES, RP .
AMERICAN JOURNAL OF MEDICINE, 1991, 91 :S72-S75
[10]   Surveillance of antimicrobial resistance in Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in the United States in 1996-1997 respiratory season [J].
Thornsberry, C ;
Ogilvie, P ;
Kahn, J ;
Mauriz, Y .
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 1997, 29 (04) :249-257