Ability of antibodies to two new caliciviral vaccine strains to neutralise feline calicivirus isolates from the UK

被引:20
作者
Addie, D. [1 ]
Poulet, H. [2 ]
Golder, M. C. [1 ]
Mcdonald, M. [1 ]
Brunet, S. [2 ]
Thibault, J. -C. [2 ]
Hosie, M. J. [1 ]
机构
[1] Univ Glasgow, Fac Vet Med, Inst Comparat Med, Glasgow G61 1QH, Lanark, Scotland
[2] Merial Lyon Labs, Dept Res & Dev, F-69007 Lyon, France
基金
英国医学研究理事会; 英国生物技术与生命科学研究理事会;
关键词
D O I
10.1136/vr.163.12.355
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
This study examined a panel of 110 UK field isolates of feline calicivirus (FCV) for susceptibility to cross-neutralisation by a panel of eight antisera raised in cats infected with FCV strains F9, 255, FCVG1 and FCV431. The pairs of antisera raised against F9 or 255, neutralised 20 and 21 per cent or 37 and 56 per cent of field strains of virus respectively. In contrast, the pairs of antisera raised against the newer vaccine strains FCVG1 or FCV431 neutralised 29 and 70 per cent or 67 and 87 per cent of field strains respectively. Antisera raised against the two newer strains, namely FCVG1 and FCV431, neutralised a greater proportion of field strains of calicivirus than antisera raised against the older FCV vaccine strains F9 and 255.
引用
收藏
页码:355 / +
页数:3
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