Three-Dimensional Au/Holey-Graphene as Efficient Electrochemical Interface for Simultaneous Determination of Ascorbic Acid, Dopamine and Uric Acid

被引：11
作者：
Jing, Aihua [1 ]
Liang, Gaofeng [2 ]
Yuan, Yixin [3 ]
Feng, Wenpo [1 ]
机构：
[1] Henan Univ Sci & Technol, Sch Med Technol & Engn, Luoyang 471003, Peoples R China
[2] Henan Univ Sci & Technol, Med Coll, Luoyang 471003, Peoples R China
[3] Northeast Agr Univ, Food Sci Coll, Harbin 150030, Heilongjiang, Peoples R China
来源：
MICROMACHINES | 2019年 / 10卷 / 02期
基金：
中国国家自然科学基金;
关键词：
graphene; gold; electrochemical; ascorbic acid; dopamine; uric acid; HYDROGEN-PEROXIDE; GOLD NANOPARTICLES; HOLEY GRAPHENE; ELECTRODE; NANOCOMPOSITE; OXIDE;
D O I：
10.3390/mi10020084
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
The quantification of ascorbic acid (AA), dopamine (DA), and uric acid (UA) has been an important area of research, as these molecules' determination directly corresponds to the diagnosis and control of diseases of nerve and brain physiology. In our research, graphene oxide (GO) with nano pores deposited with gold nanoparticles were self-assembled to form three-dimensional (3D) Au/holey-graphene oxide (Au/HGO) composite structures. The as-prepared 3DAu/HGO composite structures were characterized for their structures by X-ray diffraction, Raman spectrum, scanning electron microscopy, and transmission electron microscopy coupled with cyclic voltammograms. Finally, the proposed 3DAu/HGO displayed high sensitivity, excellent electron transport properties, and selectivity for the simultaneous electrochemical determination of AA, DA and UA with linear response ranges of 1.0-500 M, 0.01-50 M and 0.05-50 M respectively. This finding paves the way for graphene applications as a biosensor for detecting three analytes in human serum.
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页数：11
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