Three-component one-pot synthesis of 4,6-diarylpyrimidin-2(1H)-ones under solvent-free conditions in the presence of sulfamic acid as a green and reusable catalyst

被引：50
作者：
Heravi, Majid M. [1 ]
Ranjbar, Leila [1 ]
Derikvand, Fatemeh [1 ]
Alimadadi, Behnoush [1 ]
机构：
[1] Alzahra Univ, Sch Sci, Dept Chem, Tehran, Iran
来源：
MOLECULAR DIVERSITY | 2008年 / 12卷 / 3-4期
关键词：
Diarylpyrimidinones; Solvent-free reactions; Solid acid catalysts; Sulfamic acid; Multi-component reactions;
D O I：
10.1007/s11030-008-9089-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A rapid and efficient one-pot method for the synthesis of 4,6-diarylpyrimidin-2(1H)-ones and related heterocycles is described. The condensation of acetophenone derivatives, aldehydes and urea in the presence of sulfamic acid was employed to synthesize a variety of pyrimidinones in moderate to excellent yields. The scope and limitations of this method are described.
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收藏
页码：191 / 196
页数：6
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