Recent advances in antiviral nucleoside and nucleotide therapeutics

被引:53
作者
Simons, C
Wu, QP
Htar, TT
机构
[1] Cardiff Univ, Welsh Sch Pharm, Div Med Chem, Cardiff CF10 3FX, S Glam, Wales
[2] Beijing Inst Technol, Sch Life Sci & Technol, Beijing 100081, Peoples R China
[3] Univ Coll Sedaya Int, Sch Pharm, Kuala Lumpur 56100, Malaysia
关键词
nucleoside/nucleotide therapeutics; influenza virus; human immunodeficiency virus; hepatitis B and C virus; herpes virus; poxvirus; filovirus; siRNA; antisense oligonucleotides;
D O I
10.2174/156802605774463051
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Recent developments in nucleoside/nucleotide therapeutics and antiviral drug targets are described covering progress in the development of nucleoside/nucleotide mimetics for the treatment of influenza virus, human immunodeficiency virus type 1, hepatitis B and C virus, herpes virus infections; including herpes simplex virus, cytomegalovirus and varicella zoster virus infections, and the highly pathogenic poxviruses (variola, vaccinia and mokey pox) and filoviruses (Ebola and Marburg).
引用
收藏
页码:1191 / 1203
页数:13
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