Synthesis of novel 2-cyanothiazolocarbazoles analogues of ellipticine

被引:31
作者
Chabane, H
Lamazzi, C
Thiéry, V
Guillaumet, G
Besson, T
机构
[1] Univ Rochelle, Lab Genie Prot & Cellulaire, Grp Chim Organ, UFR Sci Fondamentales & Sci, F-17042 La Rochelle 1, France
[2] Univ Orleans, CNRS, UMR 6005, Inst Chim Organ & Analyt, F-45067 Orleans, France
关键词
ellipticine analogues; 4,5-dichloro-1,2,3-dithiazolium chloride; thiazolocarbazoles;
D O I
10.1016/S0040-4039(02)00353-2
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Novel linear thiazolocarbazoles, which are structurally very close to the natural alkaloid ellipticine, have been rapidly synthesised via imino-1,2,3-dithiazoles, themselves readily obtained by treatment of the appropriate 3-aminocarbazoles with 4,5-dichloro-1,2,3-dithiazolium chloride 1 (Appel salt). (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:2483 / 2486
页数:4
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