Platelet-rich plasma for the treatment of chronic rectal ulcer: A case report

被引：1

作者：

Liu, Gengjun ^{[1
]}

Li, Ying ^{[1
]}

Li, Yaxin ^{[1
]}

Wang, Licun ^{[1
]}

Li, Ping ^{[1
]}

Liu, Zheng ^{[1
]}

Liu, Jiao ^{[1
]}

Ge, Dongmei ^{[1
]}

Zhao, Gang ^{[2
]}

Wang, Haiyan ^{[1
]}

机构：

[1] Qingdao Univ, Affiliated Hosp, Dept Blood Transfus, Qingdao 266000, Shandong, Peoples R China

[2] Qingdao Univ, Affiliated Hosp, Dept Anorectal Surg, Qingdao 266000, Shandong, Peoples R China

来源：

MEDICINE | 2022年 / 101卷 / 41期

基金：

中国国家自然科学基金;

关键词：

case report; platelet-rich plasma (PRP); rectal ulcer; wound healing; PERIANAL FISTULAS; ADVANCEMENT FLAP; PRP; GEL;

D O I：

10.1097/MD.0000000000030016

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Rationale: Rectum ulcer is a disease of the digestive system, the main symptoms of which includes bloody diarrhea, abdominal pain, hematochezia, etc. At present, drug therapy and surgery are the most common treatments. Platelet-rich plasma (PRP) contains high concentrations of platelets and has been used to promote wound healing. However, the utilization of PRP in rectal ulcers has rarely been reported. Patient concerns: The patient had reported a complaint of blood dripping from the stool for more than 4 months. She had a history of surgery for rectal cancer with postoperative chemotherapy and radiotherapy 19 years prior. Mesalazine suppository was given to her for about 4 months, and glutamine capsules for 2 months, but the rectal ulcer remained unhealed. Diagnosis: A rectal ulcer was observed on colonoscopy, and the biopsy result was tubular adenoma. Interventions: Autologous PRP treatment was performed for the patient under an anorectal scope together with basic supportive care. Outcomes: The ulcer nearly healed within 9 days after twice PRP treatments. Lessons: PRP treatment may bring about novel treatment options for rectal ulcers.

引用

页数：5