Redox biology of blood revisited: The role of red blood cells in maintaining circulatory reductive capacity

被引:39
作者
Buehler, PW [1 ]
Alayash, AI [1 ]
机构
[1] US FDA, CBER, NIH, Lab Biochem & Vasc Biol,Div Hematol, Bethesda, MD 20892 USA
关键词
D O I
10.1089/ars.2005.7.1755
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
There is an increasing recognition of the role of red blood cells (RBCs) in cell signaling above and beyond its oxygen (O-2)-carrying function. A recent forum published in the December 2004 issue of Antioxidants & Redox Signaling focused on redox biology of blood and the intricate signaling pathways of RBCs or its free components, i.e., hemoglobin, with the vasculature. The forum provided an up-to-date source of information on this emerging and exciting area of blood biology and the underlying redox chemistry. In the current short review, we have revisited the topic of redox biology of blood and focused on yet another emerging area of research, which deals with the reductive power of blood and the physiological implications.
引用
收藏
页码:1755 / 1760
页数:6
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