Phosphine-Catalyzed Rauhut-Currier Domino Reaction: A Facile Strategy for the Construction of Carbocyclic Spirooxindoles Skeletons

被引：32
|
作者：
Hu, Chongchong [1 ,2 ]
Zhang, Qinglong [1 ,2 ]
Huang, You [1 ,2 ]
机构：
[1] Nankai Univ, State Key Lab, Tianjin 300071, Peoples R China
[2] Nankai Univ, Inst Elementoorgan Chem, Tianjin 300071, Peoples R China
来源：
CHEMISTRY-AN ASIAN JOURNAL | 2013年 / 8卷 / 09期
基金：
中国国家自然科学基金;
关键词：
catalysis; conjugation; domino reactions; phosphines; spiro compounds; STRUCTURE-BASED DESIGN; MORITA-BAYLIS-HILLMAN; HIGHLY ENANTIOSELECTIVE SYNTHESIS; 4 CONSECUTIVE STEREOCENTERS; ASYMMETRIC TOTAL-SYNTHESIS; N-THIOPHOSPHINYL IMINES; STEREOSELECTIVE-SYNTHESIS; SULFONATED IMINES; 3+2 ANNULATION; DERIVATIVES;
D O I：
10.1002/asia.201300650
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Push-over: A novel domino reaction of activated conjugated dienes and methyleneindolinones incorporates a phosphine-catalyzed intermolecular Rauhut-Currier to form two C-C bonds and a quaternary carbon center. This method can be used to synthesize spirocyclopenteneoxindoles skeletons, which are potential building blocks for biologically active compounds. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：1981 / 1984
页数：4
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