Linkage-Disequilibrium-Based Binning Misleads the Interpretation of Genome-wide Association Studies

被引:1
|
作者
Zhu, Xiaofeng [1 ]
Feng, Tao [1 ]
Elston, Robert C. [1 ]
机构
[1] Case Western Reserve Univ, Sch Med, Dept Epidemiol & Biostat, Cleveland, OH 44106 USA
关键词
D O I
10.1016/j.ajhg.2012.05.029
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
引用
收藏
页码:965 / 968
页数:4
相关论文
共 50 条
  • [41] Genome-Wide Association Studies
    Guo, Xiuqing
    Rotter, Jerome I.
    JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2019, 322 (17): : 1705 - 1706
  • [42] Genome-wide linkage disequilibrium analysis in bread wheat and durum wheat
    Somers, Daryl J.
    Banks, Travis
    DePauw, Ron
    Fox, Stephen
    Clarke, John
    Pozniak, Curtis
    McCartney, Curt
    GENOME, 2007, 50 (06) : 557 - 567
  • [43] Nonlinear analysis of time series in genome-wide linkage disequilibrium data
    Hernandez-Lemus, Enrique
    Estrada-Gil, Jesus K.
    Silva-Zolezzi, Irma
    Fernandez-Lopez, J. Carlos
    Hidalgo-Miranda, Alfredo
    Jimenez-Sanchez, Gerardo
    BIOLOGICAL PHYSICS, 2008, 978 : 34 - +
  • [44] Robust Tests in Genome-Wide Scans under Incomplete Linkage Disequilibrium
    Zheng, Gang
    Joo, Jungnam
    Zaykin, Dmitri
    Wu, Colin
    Geller, Nancy
    STATISTICAL SCIENCE, 2009, 24 (04) : 503 - 516
  • [45] Extent and genome-wide distribution of linkage disequilibrium in commercial maize germplasm
    Van Inghelandt, Delphine
    Reif, Jochen C.
    Dhillon, Baldev S.
    Flament, Pascal
    Melchinger, Albrecht E.
    THEORETICAL AND APPLIED GENETICS, 2011, 123 (01) : 11 - 20
  • [46] Genome-wide linkage disequilibrium in the Blonde d'Aquitaine cattle breed
    Beghain, J.
    Boitard, S.
    Weiss, B.
    Boussaha, M.
    Gut, I.
    Rocha, D.
    JOURNAL OF ANIMAL BREEDING AND GENETICS, 2013, 130 (04) : 294 - 302
  • [47] Extent and genome-wide distribution of linkage disequilibrium in commercial maize germplasm
    Delphine Van Inghelandt
    Jochen C. Reif
    Baldev S. Dhillon
    Pascal Flament
    Albrecht E. Melchinger
    Theoretical and Applied Genetics, 2011, 123 : 11 - 20
  • [48] Genome-wide linkage disequilibrium in two Japanese beef cattle breeds
    Odani, M
    Narita, A
    Watanabe, T
    Yokouchi, K
    Sugimoto, Y
    Fujita, T
    Oguni, T
    Matsumoto, M
    Sasaki, Y
    ANIMAL GENETICS, 2006, 37 (02) : 139 - 144
  • [49] Genome-wide linkage disequilibrium in a Thai multibreed dairy cattle population
    Laodim, Thawee
    Koonawootrittriron, Skorn
    Elzo, Mauricio A.
    Suwanasopee, Thanathip
    LIVESTOCK SCIENCE, 2015, 180 : 27 - 33
  • [50] Genome-Wide Linkage Disequilibrium in Nine-Spined Stickleback Populations
    Yang, Ji
    Shikano, Takahito
    Li, Meng-Hua
    Merila, Juha
    G3-GENES GENOMES GENETICS, 2014, 4 (10): : 1919 - 1929