Medicinal plants and cancer chemoprevention

被引：333

作者：

Desai, Avni G. ^{[1
]}

Qazi, Ghulam N. ^{[4
]}

Ganju, Ramesh K. ^{[3
]}

El-Tamer, Mahmoud ^{[2
]}

Singh, Jaswant ^{[4
]}

Saxena, Ajit K. ^{[4
]}

Bedi, Yashbir S. ^{[4
]}

Taneja, Subhash C. ^{[4
]}

Bhat, Hari K. ^{[1
]}

机构：

[1] Columbia Univ, Mailman Sch Publ Hlth, Dept Environm Hlth Sci, New York, NY 10032 USA

[2] Columbia Univ, Coll Phys & Surg, Dept Surg, New York, NY 10032 USA

[3] Ohio State Univ, Dept Pathol, Columbus, OH 43210 USA

[4] Council Sci & Ind Res Jammu Tawi, Indian Inst Integrat Med, Jammu, India

来源：

CURRENT DRUG METABOLISM | 2008年 / 9卷 / 07期

关键词：

medicinal plants; natural products; ayurveda; cancer; alternative medicine;

D O I：

10.2174/138920008785821657

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cancer is the second leading cause of death worldwide. Although great advancements have been made in the treatment and control of cancer progression, significant deficiencies and room for improvement remain. A number of undesired side effects sometimes occur during chemotherapy. Natural therapies, such as the use of plant-derived products in cancer treatment, may reduce adverse side effects. Currently, a few plant products are being used to treat cancer. However, a myriad of many plant products exist that have shown very promising anti-cancer properties in vitro, but have yet to be evaluated in humans. Further study is required to determine the efficacy of these plant products in treating cancers in humans. This review will focus on the various plant-derived chemical compounds that have, in recent years, shown promise as anticancer agents and will outline their potential mechanism of action.

引用

页码：581 / 591

页数：11

共 135 条

[21]

Dikshit A, 1982, INDIAN PERFUMER, V26, P216

[22] Immunoprotection by botanical drugs in cancer chemotherapy [J].

Diwanay, S ;

Chitre, D ;

Patwardhan, B .

JOURNAL OF ETHNOPHARMACOLOGY, 2004, 90 (01) :49-55

[23] Induction of apoptosis by curcumin:: mediation by glutathione S-transferase P1-1 inhibition [J].

Duvoix, A ;

Morceau, F ;

Delhalle, S ;

Schmitz, M ;

Schnekenburger, M ;

Galteau, MM ;

Dicato, M ;

Diederich, M .

BIOCHEMICAL PHARMACOLOGY, 2003, 66 (08) :1475-1483

[24]

Eiznhamer DA, 2004, IDRUGS, V7, P359

[25] CYCLOPHOSPHAMIDE TOXICITY - CHARACTERIZING AND AVOIDING THE PROBLEM [J].

FRAISER, LH ;

KANEKAL, S ;

KEHRER, JP .

DRUGS, 1991, 42 (05) :781-795

[26] Sensitization for anticancer drug-induced apoptosis by betulinic acid [J].

Fulda, S ;

Debatin, KM .

NEOPLASIA, 2005, 7 (02) :162-170

[27]

Gangan VD, 1997, INDIAN J CHEM B, V36, P787

[28] Glycosidation of lupane-type triterpenoids as potent in vitro cytotoxic agents [J].

Gauthier, Charles ;

Legault, Jean ;

Lebrun, Maxime ;

Dufour, Philippe ;

Pichette, Andr .

BIOORGANIC & MEDICINAL CHEMISTRY, 2006, 14 (19) :6713-6725

[29] INCREASED BONE-MARROW TOXICITY OF DOXORUBICIN BOUND TO NANOPARTICLES [J].

GIBAUD, S ;

ANDREUX, JP ;

WEINGARTEN, C ;

RENARD, M ;

COUVREUR, P .

EUROPEAN JOURNAL OF CANCER, 1994, 30A (06) :820-826

[30] Boswellic acids and malignant glioma: induction of apoptosis but no modulation of drug sensitivity [J].

Glaser, T ;

Winter, S ;

Groscurth, P ;

Safayhi, H ;

Sailer, ER ;

Ammon, HPT ;

Schabet, M ;

Weller, M .

BRITISH JOURNAL OF CANCER, 1999, 80 (5-6) :756-765

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