Enantioselective Chemo- nd Biocatalysis: Partners in Retrosynthesis

被引：208

作者：

Honig, Moritz ^{[1
]}

Sondermann, Philipp ^{[1
]}

Turner, Nicholas J. ^{[2
,3
]}

Carreira, Erick M. ^{[1
]}

机构：

[1] Swiss Fed Inst Technol, Lab Organ Chem, Vladimir Prelog Weg 3, CH-8093 Zurich, Switzerland

[2] Univ Manchester, Manchester Inst Biotechnol, 131 Princess St, Manchester M1 7DN, Lancs, England

[3] Univ Manchester, Sch Chem, 131 Princess St, Manchester M1 7DN, Lancs, England

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2017年 / 56卷 / 31期

基金：

瑞士国家科学基金会; 欧洲研究理事会;

关键词：

biocatalysis; catalysis; enantioselectivity; retrosynthesis; ALPHA-AMINO-ACIDS; CATALYTIC ASYMMETRIC-SYNTHESIS; C-H OXIDATION; HIGHLY EFFICIENT AMINOHYDROXYLATION; HYDROLYTIC KINETIC RESOLUTION; BETA-HYDROXYISOBUTYRIC ACID; ENZYME ACE INHIBITORS; AZA-HENRY REACTION; ONE-POT SYNTHESIS; ALLYLIC AMINATION;

D O I：

10.1002/anie.201612462

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Recent developments of stereoselective biocatalytic and chemo-catalytic methods are discussed. The review provides a guide to the use of biocatalytic methods in the area of chemical synthesis with focused attention on retrosynthetic considerations and analysis. The transformations presented are organized according to bond disconnections and attendant synthetic methods. The review is expected to lead to better understanding of the characteristics and distinctions of the two complementary approaches. It depicts for researchers in bio- and chemocatalysis a road map of challenges and opportunities for the evolution (and at times revolution) in chemical synthesis.

引用

页码：8942 / 8973

页数：32

共 419 条

[1]

Abrahamson M.J., 2012, ANGEW CHEM, V124, P4036, DOI [DOI 10.1002/ANGE.201107813, 10.1002/ange.201107813]

[2] Development of an Amine Dehydrogenase for Synthesis of Chiral Amines [J].

Abrahamson, Michael J. ;

Vazquez-Figueroa, Eduardo ;

Woodall, Nicholas B. ;

Moore, Jeffrey C. ;

Bommarius, Andreas S. .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2012, 51 (16) :3969-3972

[3] Immobilized Bisdiazaphospholane Catalysts for Asymmetric Hydroformylation [J].

Adint, Tyler T. ;

Landis, Clark R. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2014, 136 (22) :7943-7953

[4] Achieving Regio- and Enantioselectivity of P450-Catalyzed Oxidative CH Activation of Small Functionalized Molecules by Structure-Guided Directed Evolution [J].

Agudo, Ruben ;

Roiban, Gheorghe-Doru ;

Reetz, Manfred T. .

CHEMBIOCHEM, 2012, 13 (10) :1465-1473

[5]

Andersson M. A., 2002, ANGEW CHEM, V114, P490

[6]

Andersson MA, 2002, ANGEW CHEM INT EDIT, V41, P472, DOI 10.1002/1521-3773(20020201)41:3<472::AID-ANIE472>3.0.CO

[7]

2-7

[8] Highly enantioselective copper-bisoxazoline-catalyzed allylic oxidation of cyclic olefins with tert-butyl p-nitroperbenzoate [J].

Andrus, MB ;

Zhou, ZN .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (30) :8806-8807

[9] THE ASYMMETRIC KHARASCH REACTION - CATALYTIC ENANTIOSELECTIVE ALLYLIC ACYLOXYLATION OF OLEFINS WITH CHIRAL COPPER(I) COMPLEXES AND TERT-BUTYL PERBENZOATE [J].

ANDRUS, MB ;

ARGADE, AB ;

CHEN, X ;

PAMMENT, MG .

TETRAHEDRON LETTERS, 1995, 36 (17) :2945-2948

[10] Polymer-supported chiral Co(salen) complexes: Synthetic applications and mechanistic investigations in the hydrolytic kinetic resolution of terminal epoxides [J].

Annis, DA ;

Jacobsen, EN .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (17) :4147-4154

← 1 2 3 4 5 6 7 8 9 10 →