共 21 条
Renal angiomyolipoma with minimal fat: Differentiation trom other neoplasms at double-echo chemical shift FLASH MR imaging
被引:130
作者:
Kim, JK
Kim, SH
Jang, YJI
Ahn, H
Kim, CS
Park, H
Lee, JW
Kim, S
Cho, KS
机构:
[1] Univ Ulsan, Dept Radiol, Asan Med Ctr, Seoul 138736, South Korea
[2] Univ Ulsan, Dept Urol, Asan Med Ctr, Seoul 138736, South Korea
[3] Pusan Natl Univ Hosp, Dept Radiol, Pusan, South Korea
来源:
关键词:
D O I:
10.1148/radiol.2391050102
中图分类号:
R8 [特种医学];
R445 [影像诊断学];
学科分类号:
1002 ;
100207 ;
1009 ;
摘要:
Purpose: To prospectively evaluate the diagnostic performance or double-echo gradient-echo (GRE) chemical shift magnetic resonance (MR) imaging in the differentiation of angiomyolipoma (AML) with minimal fat front other renal neoplasms. with pathologic examination or follow-Lip data serving as the reference standard. Materials and methods: Institutional review board approval and informed consent were obtained-Double-echo GRE chemical shift MR imaging was performed in 55 patients (29 men and 26 women; mean age, 49 years +/- 14 [standard deviation]) with 55 renal tumors, including 37 (67%) pathologically proved tumors (23 renal cell carcinomas, nine AMLs. two oncocytomas, two lymphomas, and one reninoma) and 18 (33%) clinically diagnosed tumors (17 AMLs and one indeterminate malignancy). All tumors showed no intratumoral Fat and had homogeneous enhancement and a prolonged or gradual enhancement pattern on biphasic helical computed tomographic scans. Signal intensity was measured in the renal tumor and spleen on in-phase and opposed-phase images. The signal intensity index and tumor-to-spleen ratio in AMLs and non-AMLs were calculated and compared with the Student t test. Receiver operating characteristic (ROC) analysis was performed to evaluate the diagnostic accuracy of the signal intensity index and tumor-to-spleen ratio and to extract. the optimal cut-off values in the differentiation of AMLs and non-AMLs. Results: The signal intensity index and tumor-to-spleen ratio were different between AMLs (42% +/- 11 and -43% +/- 17, respectively) and non-AMLs (5% +/- 14 and -4% +/- 16, respectively) (P < .001). The area under the ROC curve was 0.975 for the signal intensity index and 0.952 for the tumor-to-spleen ratio. For differentiation of AMLs from non-AMLs, sensitivity and specificity were (a) 96% and 93%, respectively, with a signal intensity index of 25% and (b) 88% and 97%, respectively, with a tumor-to-spleen ratio or -32%. Conclusion: Double-echo GRE chemical shift, NIB imaging can be used to differentiate AML, with minimal fat from other renal neoplasms. (c) RSNA, 2006.
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页码:174 / 180
页数:7
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