Antibacterial diterpenoid acids from Azorella compacta

被引：37

作者：

Wächter, GA

Matooq, G

Hoffmann, JJ

Maiese, WM

Singh, MP

Montenegro, G

Timmermann, BN ^{[1
]}

机构：

[1] Univ Arizona, Coll Pharm, Dept Pharmacol & Toxicol, Tucson, AZ 85721 USA

[2] Univ Arizona, Coll Agr, Bioresources Res Facil, Tucson, AZ 85721 USA

[3] Wyeth Ayerst Res Labs, Nat Prod Res Sect, Pearl River, NY 10965 USA

[4] Pontificia Univ Catolica Chile, Dept Ecol, Santiago, Chile

来源：

JOURNAL OF NATURAL PRODUCTS | 1999年 / 62卷 / 09期

关键词：

D O I：

10.1021/np990134u

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The two novel diterpenoid acids mulin-12,14-dien-11-on-20-oic acid (1) and mulin-12-ene-11,14-dion-20-oic acid (2) have been isolated from Azorella compacta. Their structures have been elucidated by 1D and 2D NMR methods. In contrast to the closely related known mulinolic acid (3) and its dehydration product (4) these new natural products have been shown to exhibit antimicrobial activity.

引用

页码：1319 / 1321

页数：3

共 5 条

[1]

HOFFMANN A, 1992, PLANTAS MED USO COMU, P116

[2] Diterpenoids from Azorella compacta [J].