Protein crystal growth in microgravity using a liquid/liquid diffusion method

被引:1
作者
Wang, YP [1 ]
Han, Y [1 ]
Pan, JS [1 ]
Wang, KY [1 ]
Bi, RC [1 ]
机构
[1] CHINESE ACAD SCI,SHANGHAI INST BIOCHEM,SHANGHAI 200031,PEOPLES R CHINA
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D O I
暂无
中图分类号
V [航空、航天];
学科分类号
08 ; 0825 ;
摘要
Crystallization of proteins by liquid/liquid diffusion method was performed in microgravity using the MDA Minilab aboard the US Space Shuttle. Three proteins, namely lysozyme, trichosanthin, and a new lechin, were crystallized in the space experiment. In contrast to the results of space experiments with a tube-like vapor diffusion method, the crystallization conditions for growing better crystals in space are remarkably different from the conditions optimized on earth. This may be due to difficulties in ground optimization, which are caused by gravity-dependent phenomena, in particular the specific convective flow occurring with liquid/liquid diffusion.
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页码:281 / 283
页数:3
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