Dissociative Tremor Response with Pallidal Deep Brain Stimulation in Parkinson's Disease

被引：0

作者：

Wang, Anson ^{[1
]}

Molho, Eric ^{[2
]}

Yang, Yingmai ^{[1
,3
]}

Pilitsis, Julie ^{[4
,5
]}

Ramirez-Zamora, Adolfo ^{[1
]}

机构：

[1] Univ Florida, Dept Neurol, Gainesville, FL 32611 USA

[2] Albany Med Ctr, Dept Neurol, Albany, NY USA

[3] Peking Union Med Coll Hosp, Beijing, Peoples R China

[4] Albany Med Ctr, Dept Neurosurg, Albany, NY USA

[5] Albany Med Coll, Dept Neurosci & Expt Therapeut, Albany, NY 12208 USA

来源：

TREMOR AND OTHER HYPERKINETIC MOVEMENTS | 2020年 / 10卷

基金：

美国国家卫生研究院;

关键词：

Deep brain stimulation; GPi; VIM; Tremor; Parkinson's disease; SUBTHALAMIC NUCLEUS; THALAMIC-STIMULATION; GLOBUS-PALLIDUS;

D O I：

10.5334/tohm.568

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background: Pallidal and subthalamic targets are commonly used for deep brain stimulation in Parkinson's disease (PD), with similar efficacy for resting tremor control. However, neuromodulatory effects on kinetic and postural tremor in PD is less clear. Case Report: We present a 67-year-old PD patient with marked dissociative tremor response following pallidal neuromodulation. We observed excellent resting tremor suppression, but postural and kinetic tremors remained severe, requiring additional thalamic VIM stimulation for management. Discussion: Our findings illustrate the phenotypical differences in PD and differential response to diverse tremor characteristics with distinctive stimulation targets. Additional studies are necessary to understand these differences.

引用

页码：1 / 5

页数：5

共 20 条

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