Interference of a carbamoyl glucuronide metabolite in quantitative liquid chromatography/tandem mass spectrometry

被引:28
作者
Liu, DQ [1 ]
Pereira, T [1 ]
机构
[1] Merck Res Labs, Dept Drug Metab, Rahway, NJ 07065 USA
关键词
D O I
10.1002/rcm.549
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:142 / 146
页数:5
相关论文
共 17 条
[1]  
BROWN SY, 1990, DRUG METAB DISPOS, V18, P546
[2]   Determination of a thermally labile metabolite of a novel growth hormone secretagogue in human and dog plasma by liquid chromatography with ion spray tandem mass spectrometric detection [J].
Constanzer, M ;
Chavez-Eng, C ;
Matuszewski, B .
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2001, 760 (01) :45-53
[3]   ON THE FORMATION OF CARBAMATE GLUCURONIDES [J].
DELBRESSINE, LPC ;
FUNKE, CW ;
VANTILBORG, M ;
KASPERSEN, FM .
XENOBIOTICA, 1990, 20 (01) :133-134
[4]  
DOW J, 1994, DRUG METAB DISPOS, V22, P738
[5]   TOCAINIDE CONJUGATION IN HUMANS - NOVEL BIOTRANSFORMATION PATHWAY FOR A PRIMARY AMINE [J].
ELVIN, AT ;
KEENAGHAN, JB ;
BYRNES, EW ;
TENTHOREY, PA ;
MCMASTER, PD ;
TAKMAN, BH ;
LALKA, D ;
MANION, CV ;
BAER, DT ;
WOLSHIN, EM ;
MEYER, MB ;
RONFELD, RA .
JOURNAL OF PHARMACEUTICAL SCIENCES, 1980, 69 (01) :47-49
[6]  
Jemal M, 1999, RAPID COMMUN MASS SP, V13, P97, DOI 10.1002/(SICI)1097-0231(19990130)13:2<97::AID-RCM461>3.0.CO
[7]  
2-T
[8]   Use of on-line hydrogen/deuterium exchange to facilitate metabolite identification [J].
Liu, DQ ;
Hop, CECA ;
Beconi, MG ;
Mao, A ;
Chiu, SHL .
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2001, 15 (19) :1832-1839
[9]   Matrix effect in quantitative LC/MS/MS analyses of biological fluids: A method for determination of finasteride in human plasma at picogram per milliliter concentrations [J].
Matuszewski, BK ;
Constanzer, ML ;
Chavez-Eng, CM .
ANALYTICAL CHEMISTRY, 1998, 70 (05) :882-889
[10]   Disposition of ropinirole in animals and man [J].
Ramji, JV ;
Keogh, JP ;
Blake, TJ ;
Broom, C ;
Chenery, RJ ;
Citerone, DR ;
Lewis, VA ;
Taylor, AC ;
Yeulet, SE .
XENOBIOTICA, 1999, 29 (03) :311-325