Difference of mineral contents in human intervertebral disks and its age-related change

被引:43
作者
Tohno, S [1 ]
Tohno, Y [1 ]
Minami, T [1 ]
Ichii, M [1 ]
Okazaki, Y [1 ]
Utsumi, M [1 ]
Nishiwaki, F [1 ]
Yamada, MO [1 ]
机构
[1] KINKI UNIV,FAC PHARMACEUT SCI,HIGASHIOSAKA,OSAKA 577,JAPAN
关键词
intervertebral disk; aging; calcium; phosphorus; mineral element; human; vertebral column;
D O I
10.1007/BF02789453
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
To establish a difference of the relative contents (RCs) of elements among the cervical, thoracic, and lumbar intervertebral disks and its age-related change, the intervertebral disks between the axis and the sacrum, which were resected from the nine cadavers who died at 53 to 99 yr old, were analyzed by inductively coupled atomic plasma emission spectrometry. It was found that both the RCs of calcium and phosphorus were high in the cervical disks, especially the highest in the disk between the 6th and 7th cervical vertebrae, and lower in the order of the cervical, thoracic, and lumbar intervertebral disks. In regard to the RCs of sulfur and magnesium, there were no significant differences among the cervical, thoracic, and lumbar intervertebral disks. In addition, it was found that both the RCs of calcium and phosphorus in the cervical intervertebral disks started to increase in the sixth decade of life, became the highest in the eighth decade of life, and then decreased.
引用
收藏
页码:117 / 124
页数:8
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