Salivary steroids in response to ACTH - A less invasive approach to assess adrenal function in hypotensive patients with chronic renal failure

被引：6

作者：

Contreras, LN

Arregger, AL

Tumilasci, O

Persi, G

Zucchini, A

Cardoso, EM

机构：

[1] Univ Buenos Aires, Inst Invest Med A Lanari, Dept Nephrol, RA-1427 Buenos Aires, DF, Argentina

[2] Consejo Nacl Invest Cient & Tecn, Consejo Nacl Invest Cient & Tecn, RA-1033 Buenos Aires, DF, Argentina

[3] Univ Buenos Aires, Sch Med, Salivary Glands Lab, RA-1053 Buenos Aires, DF, Argentina

[4] Univ Buenos Aires, Dept Endocrine Res, RA-1053 Buenos Aires, DF, Argentina

来源：

ENDOCRINOLOGIST | 2006年 / 16卷 / 01期

关键词：

ACTH test; salivary steroids; chronic renal failure; hypotension;

D O I：

10.1097/01.ten.0000194248.85361.bf

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The aim of this study was to use salivary cortisol and salivary aldosterone after an ACTH stimulation test to assess adrenal function in patients with chronic renal failure (CRF). Salivary samples for the measurement of cortisol and aldosterone were obtained before and after stimulation with 250 mu g ACTH intramus cularly. Twenty patients with chronic renal failure and 24 healthy subjects were enrolled in the study. Salivary cortisol and salivary aldosterone concentrations were measured at baseline and 30 minutes after ACTH stimulation. Adrenal insufficiency was diagnosed in 5 patients. Selective hypoaldosteronism was found in 4 patients. The salivary steroid measurement after ACTH stimulation proves to be a useful test to diagnose adrenal insufficiency in patients with renal failure.

引用

页码：30 / 35

页数：6

共 48 条

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