Gold Nanoparticles - based Colorimetric Single Nucleotide Polymorphisms Genotyping Utilizing Allele-specific PCR

被引：0

作者：

Jung, Ye Lim ^{[1
]}

Jung, Cheulhee ^{[1
]}

Parab, Harshala ^{[1
]}

Park, Hyun Gyu ^{[1
]}

机构：

[1] Korea Adv Inst Sci & Technol, Dept Chem & Biomol Engn, Taejon 305701, South Korea

来源：

5TH EUROPEAN CONFERENCE OF THE INTERNATIONAL FEDERATION FOR MEDICAL AND BIOLOGICAL ENGINEERING, PTS 1 AND 2 | 2012年 / 37卷

关键词：

Single nucleotide polymorphism (SNP); allele-specific PCR; thiolated primer; gold nanoparticles; BRCA; ZIP-CODE MICROARRAY; MUTATION DETECTION; SNPS DETECTION; DNA; DIAGNOSIS; PNA; EXTENSION; NUCLEASE;

D O I：

暂无

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

A very convenient colorimetric method for the identification of single nucleotide polymorphism was developed utilizing gold nanoparticles and an allele-specific polymerase chain reaction and its diagnostic capability was successfully verified by correctly identifying various mutations in the BRCA1 gene.

引用

页码：1062 / 1065

页数：4

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