Interleukin 6 and C-reactive protein in esophageal cancer

被引：48

作者：

Groblewska, Magdalena ^{[1
]}

Mroczko, Barbara ^{[1
]}

Sosnowska, Dorota ^{[2
]}

Szmitkowski, Maciej ^{[1
]}

机构：

[1] Med Univ, Dept Biochem Diagnost, PL-15269 Bialystok, Poland

[2] Solec Hosp, Dept Gynecol & Obstet, PL-00382 Warsaw, Poland

来源：

CLINICA CHIMICA ACTA | 2012年 / 413卷 / 19-20期

关键词：

Esophageal cancer; Adenocarcinoma of esophagus; Esophageal squamous cell cancer; Interleukin; 6; C-reactive protein; SQUAMOUS-CELL CARCINOMA; PREOPERATIVE SERUM INTERLEUKIN-6; ACUTE-PHASE RESPONSE; BARRETTS-ESOPHAGUS; MULTIPLE-MYELOMA; POOR-PROGNOSIS; GASTRIC-CANCER; BREAST-CANCER; GROWTH-FACTOR; IN-VITRO;

D O I：

10.1016/j.cca.2012.05.009

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Esophageal cancer (EC) is one of the most aggressive malignant tumors of the gastrointestinal tract. It is well known that cancer initiation and tumor development are closely linked with inflammation. C-reactive protein (CRP) and interleukin-6 (IL-6) are acute-phase proteins involved in cancer development. It was suggested that CRP and IL-6 play potential roles in the growth and progression of malignant tumors, including EC. The aim of the study was to describe the significance of IL-6 and CRP in the development of esophageal cancer and to assess the potential role of their serum levels as prognostic indicators of EC patient's survival. (c) 2012 Elsevier B.V. All rights reserved.

引用

页码：1583 / 1590

页数：8

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