The investigation of the alkylation reactions of hydroxy and En-oximes with some halohydrins and epoxides

被引:7
作者
Kurbanli, S [1 ]
Sen, N [1 ]
Güler, E [1 ]
Koçak, A [1 ]
机构
[1] Selcuk Univ, Fac Arts & Sci, Dept Chem, TR-42031 Konya, Turkey
关键词
halohydrins; epoxides; ethers; oximes;
D O I
10.1081/SCC-120030754
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Suitable glycol ethers (3a-d, 4a-d) and halohydrine compounds (11a-c) were synthesized in good yield by the alkylation reactions of the oximes, having hydroxy and double bond in its structure, with mono- and dihalogenhydrines in the medium of basic and solid-liquid phase transfer catalyst. A series of aminoalcohols were synthesized from these compounds obtained (16a, 17b, 18b).
引用
收藏
页码:1663 / 1675
页数:13
相关论文
共 20 条
[1]  
[Anonymous], [No title captured]
[2]  
[Anonymous], [No title captured]
[3]  
BROWN DS, 1995, TETRAHEDRON, V51, P11473
[4]  
BURUNO JR, 1962, HELV CHIM ACTA, V45, P358
[5]   Stereoselective synthesis of alpha-hydroxy-beta-amino acids using D-glyceraldehyde as the homochiral source. [J].
Cativiela, C ;
DiazDeVillegas, MD ;
Galvez, JA .
TETRAHEDRON-ASYMMETRY, 1996, 7 (02) :529-536
[6]  
Guler E, 1998, ORG PREP PROCED INT, V30, P195
[7]  
HODGSON DM, 1996, FARMACO, V4, P251
[8]  
JEN T, 1977, J MED CHEM, V20, P693, DOI 10.1021/jm00215a015
[9]  
KAMAI GK, 1968, ZH ORG KHIM, V4, P567
[10]  
KAMAY GH, 1970, ORG KHIM, V6, P394