Potential Therapeutic Role of Phosphodiesterase Type 5 Inhibition in Hypertension and Chronic Kidney Disease

被引：23
作者：
Brown, Kayleigh E. [1 ]
Dhaun, Neeraj [1 ,2 ]
Goddard, Jane [1 ,2 ]
Webb, David J. [1 ]
机构：
[1] Univ Edinburgh, Queens Med Res Inst, British Heart Fdn Ctr Cardiovasc Sci, Edinburgh EH16 4TJ, Midlothian, Scotland
[2] Royal Infirm Edinburgh NHS Trust, Renal Unit, Edinburgh, Midlothian, Scotland
来源：
HYPERTENSION | 2014年 / 63卷 / 01期
关键词：
NITRIC-OXIDE SYNTHASE; CONVERTING ENZYME-INHIBITION; SOLUBLE GUANYLATE-CYCLASE; CHRONIC RENAL-DISEASE; BLOOD-PRESSURE CONTROL; A RECEPTOR ANTAGONISM; SILDENAFIL CITRATE; OXIDATIVE STRESS; ENDOTHELIAL DYSFUNCTION; L-ARGININE;
D O I：
10.1161/HYPERTENSIONAHA.113.01774
中图分类号：
R6 [外科学];
学科分类号：
1002 ; 100210 ;
摘要：
[No abstract available]
引用
收藏
页码：5 / 11
页数：7
相关论文
共 88 条
  • [71] Soluble Guanylate Cyclase as an Emerging Therapeutic Target in Cardiopulmonary Disease
    Stasch, Johannes-Peter
    Pacher, Pal
    Evgenov, Oleg V.
    [J]. CIRCULATION, 2011, 123 (20) : 2263 - 2273
  • [72] Renal neuronal nitric oxide synthase protein expression as a marker of renal injury
    Szabo, AJ
    Wagner, L
    Erdely, A
    Lau, K
    Baylis, C
    [J]. KIDNEY INTERNATIONAL, 2003, 64 (05) : 1765 - 1771
  • [73] Vitamin E reduces glomerulosclerosis, restores renal neuronal NOS, and suppresses oxidative stress in the 5/6 nephrectomized rat
    Tain, You-Lin
    Freshour, Gary
    Dikalova, Anna
    Griendling, Kathy
    Baylis, Chris
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2007, 292 (05) : F1404 - F1410
  • [74] RENAL METABOLISM OF AMINO-ACIDS AND AMMONIA IN SUBJECTS WITH NORMAL RENAL-FUNCTION AND IN PATIENTS WITH CHRONIC RENAL-INSUFFICIENCY
    TIZIANELLO, A
    DEFERRARI, G
    GARIBOTTO, G
    GURRERI, G
    ROBAUDO, C
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 1980, 65 (05) : 1162 - 1173
  • [75] Suppression of mesangial proliferative glomerulonephritis development in rats by inhibitors of cAMP phosphodiesterase isozymes types III and IV
    Tsuboi, Y
    Shankland, SJ
    Grande, JP
    Walker, HJ
    Johnson, RJ
    Dousa, TP
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 1996, 98 (02) : 262 - 270
  • [76] USRDS. U.S. Renal Data System, 2011, US REN DAT SYST USRD
  • [77] VALLANCE P, 1992, LANCET, V339, P572
  • [78] VALLANCE P, 1989, LANCET, V2, P997
  • [79] Downregulation of nitric oxide synthase in chronic renal insufficiency: role of excess PTH
    Vaziri, ND
    Ni, Z
    Wang, XQ
    Oveisi, F
    Zhou, XJ
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 1998, 274 (04) : F642 - F649
  • [80] Reduced nitric oxide synthase activity in rats with chronic renal disease due to glomerulonephritis
    Wagner, L
    Riggleman, A
    Erdely, A
    Couser, W
    Baylis, C
    [J]. KIDNEY INTERNATIONAL, 2002, 62 (02) : 532 - 536
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