Trimethylsilylethynyl ketones as surrogates for ethynyl ketones in the double Michael reaction

被引：9
|
作者：
Holeman, DS [1 ]
Rasne, RM [1 ]
Grossman, RB [1 ]
机构：
[1] Univ Kentucky, Dept Chem, Lexington, KY 40506 USA
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2002年 / 67卷 / 09期
关键词：
D O I：
10.1021/jo0163086
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Trimethylsilylethynyl ketones can be desilylated in the presence of a tethered carbon diacid and induced to undergo a double Michael reaction in situ. The trimethylsilylethynyl ketones can serve as surrogates of ethynyl ketones that are difficult to prepare or isolate.
引用
收藏
页码：3149 / 3151
页数：3
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