6-Mercaptopurine-induced Recurrent Acute Pancreatitis in Children With Acute Lymphoblastic Leukemia/Lymphoma

被引：7

作者：

Halalsheh, Hadeel ^{[1
]}

Bazzeh, Faiha ^{[1
]}

Alkayed, Khaldoun ^{[1
]}

Salami, Khadra ^{[1
]}

Madanat, Faris ^{[1
]}

机构：

[1] King Hussein Canc Ctr, Dept Pediat Hematol Oncol, Amman 11941, Jordan

来源：

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2013年 / 35卷 / 06期

关键词：

mercaptopurine; pancreatitis; leukemia; lymphoma; INFLAMMATORY-BOWEL-DISEASE; CROHNS-DISEASE; AZATHIOPRINE; LEUKEMIA; TOXICITY; THERAPY;

D O I：

10.1097/MPH.0b013e318271c92f

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Two children with acute lymphoblastic leukemia/lymphoma developed recurrent acute pancreatitis during treatment; the etiology was presumed to be secondary to 6-mercaptopurine (6MP). Both had no further attacks after discontinuation of 6MP. Acute pancreatitis secondary to 6MP is extremely rare in acute leukemia/lymphoma although it has been reported in patients with other conditions like inflammatory bowel disease; the reason for this difference is not clearly understood.

引用

页码：470 / 472

页数：3

共 50 条

[41] NUDT15 Polymorphism and Its Association With Mercaptopurine Hematotoxicity in Acute Lymphoblastic Leukemia in Indonesian Children
Rosdiana, Dewi Selvina
Saputri, Dianita Susilo
Louisa, Melva
Setiabudy, Rianto
IN VIVO, 2024, 38 (04): : 2041 - 2048
[42] Inherited NUDT15 Variant Is a Genetic Determinant of Mercaptopurine Intolerance in Children With Acute Lymphoblastic Leukemia
Yang, Jun J.
Landier, Wendy
Yang, Wenjian
Liu, Chengcheng
Hageman, Lindsey
Cheng, Cheng
Pei, Deqing
Chen, Yanjun
Crews, Kristine R.
Kornegay, Nancy
Wong, F. Lennie
Evans, William E.
Pui, Ching-Hon
Bhatia, Smita
Relling, Mary V.
JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (11) : 1235 - +
[43] Outcomes of children and young adults with T-cell acute lymphoblastic leukemia/lymphoma who present in critical status
Wayne, Nicole J.
Li, Yimei
Chung, Perry
Coffan, Kristin
Rheingold, Susan R.
PEDIATRIC BLOOD & CANCER, 2022, 69 (04)
[44] An exploration of mercaptopurine/methotrexate tolerance during maintenance therapy in children with acute lymphoblastic leukemia
Whiley, A. C.
Price, V
MacDonald, T.
JOURNAL OF ONCOLOGY PHARMACY PRACTICE, 2021, 27 (07) : 1631 - 1636
[45] Allopurinol to Prevent Mercaptopurine Adverse Effects in Children and Young Adults With Acute Lymphoblastic Leukemia
Kamojjala, Ruchika
Bostrom, Bruce
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2021, 43 (03) : 95 - 100
[46] Acute Lymphoblastic Leukemia in Children
Hunger, Stephen P.
Mullighan, Charles G.
NEW ENGLAND JOURNAL OF MEDICINE, 2015, 373 (16) : 1541 - 1552
[47] Skin Toxicity Due to Mercaptopurine in Maintenance Therapy Among Children With Acute Lymphoblastic Leukemia
Higgerson, Kayeleigh
Flatt, Terrie
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2023, 45 (04) : E514 - E517
[48] Comprehensive characterization of pharmacogenetic variants in TPMT and NUDT15 in children with acute lymphoblastic leukemia
Moriyama, Takaya
Yang, Wenjian
Smith, Colton
Pui, Ching-Hon
Evans, William E.
Relling, Mary, V
Bhatia, Smita
Yang, Jun J.
PHARMACOGENETICS AND GENOMICS, 2022, 32 (02) : 60 - 66
[49] Methotrexate-induced chemical meningitis in patients with acute lymphoblastic leukemia/lymphoma
Jacob, Linu A.
Sreevatsa, Aparna
Chinnagiriyappa, Lakshmaiah K.
Dasappa, Lokanatha
Suresh, T. M.
Babu, Govind
ANNALS OF INDIAN ACADEMY OF NEUROLOGY, 2015, 18 (02) : 206 - 209
[50] VARIANTS IN TPMT, ITPA, ABCC4 AND ABCB1 GENES AS PREDICTORS OF 6-MERCAPTOPURINE INDUCED TOXICITY IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA
Milosevic, Goran
Kotur, Nikola
Krstovski, Nada
Lazic, Jelena
Zukic, Branka
Stankovic, Biljana
Janic, Dragana
Katsila, Theodora
Patrinos, George P.
Pavlovic, Sonja
Dokmanovic, Lidija
JOURNAL OF MEDICAL BIOCHEMISTRY, 2018, 37 (03) : 320 - 327

← 1 2 3 4 5 →