6-Mercaptopurine-induced Recurrent Acute Pancreatitis in Children With Acute Lymphoblastic Leukemia/Lymphoma

被引：7

作者：

Halalsheh, Hadeel ^{[1
]}

Bazzeh, Faiha ^{[1
]}

Alkayed, Khaldoun ^{[1
]}

Salami, Khadra ^{[1
]}

Madanat, Faris ^{[1
]}

机构：

[1] King Hussein Canc Ctr, Dept Pediat Hematol Oncol, Amman 11941, Jordan

来源：

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2013年 / 35卷 / 06期

关键词：

mercaptopurine; pancreatitis; leukemia; lymphoma; INFLAMMATORY-BOWEL-DISEASE; CROHNS-DISEASE; AZATHIOPRINE; LEUKEMIA; TOXICITY; THERAPY;

D O I：

10.1097/MPH.0b013e318271c92f

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Two children with acute lymphoblastic leukemia/lymphoma developed recurrent acute pancreatitis during treatment; the etiology was presumed to be secondary to 6-mercaptopurine (6MP). Both had no further attacks after discontinuation of 6MP. Acute pancreatitis secondary to 6MP is extremely rare in acute leukemia/lymphoma although it has been reported in patients with other conditions like inflammatory bowel disease; the reason for this difference is not clearly understood.

引用

页码：470 / 472

页数：3

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