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Two new homoisoflavones fromPortulaca oleraceaL. and their activities
被引:27
|作者:
Duan, Yang
[1
]
Ying, Zheming
[2
]
Zhang, Mingbo
[1
]
Ying, Xixiang
[1
]
Yang, Guanlin
[2
]
机构:
[1] Liaoning Univ Tradit Chinese Med, Sch Pharm, Dalian, Peoples R China
[2] Sch First Clin, Shenyang, Peoples R China
基金:
中国国家自然科学基金;
关键词:
Portulaca oleraceaL;
homoisoflavone;
antioxidant activity;
anticholinesterase activity;
PURSLANE PORTULACA-OLERACEA;
FATTY-ACIDS;
ACTIVE-SITE;
ANTIOXIDANT;
L;
ANTICHOLINESTERASE;
FLAVONOIDS;
ACETYLCHOLINESTERASE;
EXTRACTS;
BINDING;
D O I:
10.1080/14786419.2020.1815742
中图分类号:
O69 [应用化学];
学科分类号:
081704 ;
摘要:
Two new compounds, identified as 3-(2-hydroxybenzyl)-6,8-dimethoxy-4H-chromen-4-one (1), named oleracone J and 3-(2-hydroxybenzyl)-6,8-dimethoxychroman-4-one (2), named oleracone K, were isolated fromPortulaca oleraceaL., and the structures of them were determined by spectroscopy, including one-dimensional and two-dimensional nuclear magnetic resonance, high-resolution electrospray ionisation time-of-flight mass spectrometry. The two compounds have scavenging activities in 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical quenching assay, with IC(50)values of 18.34, 23.92 mu M, and anticholinesterase activities with IC(50)values of 59.08, 67.89 mu M, respectively.
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页码:1765 / 1773
页数:9
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