Two new homoisoflavones fromPortulaca oleraceaL. and their activities

被引:27
|
作者
Duan, Yang [1 ]
Ying, Zheming [2 ]
Zhang, Mingbo [1 ]
Ying, Xixiang [1 ]
Yang, Guanlin [2 ]
机构
[1] Liaoning Univ Tradit Chinese Med, Sch Pharm, Dalian, Peoples R China
[2] Sch First Clin, Shenyang, Peoples R China
基金
中国国家自然科学基金;
关键词
Portulaca oleraceaL; homoisoflavone; antioxidant activity; anticholinesterase activity; PURSLANE PORTULACA-OLERACEA; FATTY-ACIDS; ACTIVE-SITE; ANTIOXIDANT; L; ANTICHOLINESTERASE; FLAVONOIDS; ACETYLCHOLINESTERASE; EXTRACTS; BINDING;
D O I
10.1080/14786419.2020.1815742
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Two new compounds, identified as 3-(2-hydroxybenzyl)-6,8-dimethoxy-4H-chromen-4-one (1), named oleracone J and 3-(2-hydroxybenzyl)-6,8-dimethoxychroman-4-one (2), named oleracone K, were isolated fromPortulaca oleraceaL., and the structures of them were determined by spectroscopy, including one-dimensional and two-dimensional nuclear magnetic resonance, high-resolution electrospray ionisation time-of-flight mass spectrometry. The two compounds have scavenging activities in 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical quenching assay, with IC(50)values of 18.34, 23.92 mu M, and anticholinesterase activities with IC(50)values of 59.08, 67.89 mu M, respectively.
引用
收藏
页码:1765 / 1773
页数:9
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