Quantifying Analytes in Paper-Based Microfluidic Devices Without Using External Electronic Readers

被引：130

作者：

Lewis, Gregory G. ^{[1
]}

DiTucci, Matthew J. ^{[1
]}

Phillips, Scott T. ^{[1
]}

机构：

[1] Penn State Univ, Dept Chem, State Coll, PA 16802 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2012年 / 51卷 / 51期

关键词：

analytical methods; microfluidics; paper diagnostic; point-of-care assays; sensors; LOW-COST; TIME; WAX;

D O I：

10.1002/anie.201207239

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A matter of time: Two quantitative assays are presented that require only measurements of time and the ability to see and/or count to quantify the presence of a specific analyte. The strategies rely on specific changes in wetting properties of paper when a hydrophobic detection reagent (compound 1) reacts with a desired analyte to produce hydrophilic products. This change in wetting properties enables selective and quantitative detection of the analyte. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：12707 / 12710

页数：4

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