Use of Alternative Techniques and Grafts in Urethroplasty

被引:26
作者
Browne, Brendan Michael [1 ]
Vanni, Alex J. [1 ]
机构
[1] Lahey Hosp & Med Ctr, Dept Urol, 41 Mall Rd, Burlington, MA 01805 USA
关键词
Urethral stricture; Urethroplasty; Urethral reconstruction; Injectable antifibrotic treatment; Augmentation urethroplasty; Lingual mucosa graft; Colonic mucosa graft; Tissue-engineered graft; LINGUAL MUCOSAL GRAFT; SMALL-INTESTINAL SUBMUCOSA; ANTERIOR URETHRAL STRICTURES; ENGINEERED BUCCAL MUCOSA; THICKNESS SKIN-GRAFT; TERM-FOLLOW-UP; MITOMYCIN-C; EXTRACELLULAR-MATRIX; INTERNAL URETHROTOMY; ORAL COMPLICATIONS;
D O I
10.1016/j.ucl.2016.08.003
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
The current management for complex urethral strictures commonly uses open reconstruction with buccal mucosa urethroplasty. However, there are multiple situations whereby buccal mucosa is inadequate (eg, pan-urethral stricture or prior buccal harvest) or inappropriate for utilization (eg, heavy tobacco use or oral radiation). Multiple options exist for use as alternatives or adjuncts to buccal mucosa in complex urethral strictures. This article reviews the current state of alternate techniques for urethral stricture treatment besides buccal mucosa, including injectable antifibrotic agents, augmentation urethroplasty with skin flaps, lingual mucosa, colonic mucosa, and new developments in tissue engineering for urethral graft material.
引用
收藏
页码:127 / 140
页数:14
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