Exploring the links between antibiotic occurrence, antibiotic resistance, and bacterial communities in water supply reservoirs

被引:291
作者
Huerta, Belinda [1 ]
Marti, Elisabet [1 ]
Gros, Meritxell [1 ]
Lopez, Pilar [2 ]
Pompeo, Marcelo [3 ]
Armengol, Joan [2 ]
Barcelo, Damia [1 ,4 ]
Luis Balcazar, Jose [1 ]
Rodriguez-Mozaz, Sara [1 ]
Marce, Rafael [1 ]
机构
[1] Catalan Inst Water Res ICRA, Girona 17003, Spain
[2] Univ Barcelona, Dept Ecol, FLUMEN, E-08028 Barcelona, Spain
[3] USP IBR, Dept Ecol, Sao Paulo, Brazil
[4] IDAEA CSIC, Dept Environm Chem, Barcelona 08034, Spain
关键词
Bacterial communities; Pharmaceuticals; Pollution; RDA; VETERINARY ANTIBIOTICS; MICROBIAL COMMUNITIES; AQUATIC ENVIRONMENT; GENES; RIVER; SOIL; PHARMACEUTICALS; CIPROFLOXACIN; SEDIMENTS; TRENDS;
D O I
10.1016/j.scitotenv.2013.03.071
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Antibiotic resistance represents a growing global health concern due to the overuse and misuse of antibiotics. There is, however, little information about how the selective pressure of clinical antibiotic usage can affect environmental communities in aquatic ecosystems and which bacterial groups might be responsible for dissemination of antibiotic resistance genes (ARGs) into the environment. In this study, chemical and biological characterization of water and sediments from three water supply reservoirs subjected to a wide pollution gradient allowed to draw an accurate picture of the concentration of antibiotics and prevalence of ARGs, in order to evaluate the potential role of ARGs in shaping bacterial communities, and to identify the bacterial groups most probably carrying and disseminating ARGs. Results showed significant correlation between the presence of ARG conferring resistance to macrolides and the composition of bacterial communities, suggesting that antibiotic pollution and the spreading of ARG might play a role in the conformation of bacterial communities in reservoirs. Results also pointed out the bacterial groups Actinobacteria and Firmicutes as the ones probably carrying and disseminating ARGs. The potential effect of antibiotic pollution and the presence of ARGs on the composition of bacterial communities in lacustrine ecosystems prompt the fundamental question about potential effects on bacterial-related ecosystem services supplied by lakes and reservoirs. (C) 2013 Elsevier B.V. All rights reserved.
引用
收藏
页码:161 / 170
页数:10
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