Relief from profound fatigue associated with chronic liver disease by long-term ondansetron therapy

被引：52

作者：

Jones, EA ^{[1
]}

机构：

[1] Acad Med Ctr, Dept Gastrointestinal & Liver Dis, NL-1105 AZ Amsterdam ZO, Netherlands

来源：

LANCET | 1999年 / 354卷 / 9176期

关键词：

D O I：

10.1016/S0140-6736(99)02936-0

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A woman with chronic hepatitis C and profound fatigue became symptomfree when treated long-term with ondansetron 4 mg twice daily. Altered central serotoninergic neurotransmission may contribute to fatigue complicating chronic liver disease.

引用

页码：397 / 397

页数：1

共 4 条

[1] NEUROENDOCRINE AND SUBSTRATE RESPONSES TO ALTERED BRAIN 5-HT ACTIVITY DURING PROLONGED EXERCISE TO FATIGUE [J].

BAILEY, SP ;

DAVIS, JM ;

AHLBORN, EN .

JOURNAL OF APPLIED PHYSIOLOGY, 1993, 74 (06) :3006-3012

[2]

JALAN R, 1996, GUT, V39, pA30

[3]

Jones EA, 1997, HEPATOLOGY, V25, P492

[4] EVIDENCE FOR A POSSIBLE ROLE OF 5-HYDROXYTRYPTAMINE IN THE GENESIS OF FATIGUE IN MAN - ADMINISTRATION OF PAROXETINE, A 5-HT REUPTAKE INHIBITOR, REDUCES THE CAPACITY TO PERFORM PROLONGED EXERCISE [J].

WILSON, WM ;

MAUGHAN, RJ .

EXPERIMENTAL PHYSIOLOGY, 1992, 77 (06) :921-924

← 1 →