Aspirin use and early age-related macular degeneration: a meta-analysis

被引：13

作者：

Kahawita, Shyalle K. ^{[1
]}

Casson, Robert J. ^{[1
]}

机构：

[1] Royal Adelaide Hosp, South Australian Inst Ophthalmol, Adelaide, SA 5000, Australia

来源：

CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE | 2014年 / 49卷 / 01期

关键词：

RISK-FACTORS; CUMULATIVE INCIDENCE; MACULOPATHY; PREVALENCE; CLASSIFICATION;

D O I：

10.1016/j.jcjo.2013.07.016

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Objective: The aim of this review was to evaluate the evidence for an association between Aspirin use and early age-related macular degeneration (ARMD). Methods: A literature search was performed in 5 databases with no restrictions on language or date of publication. Four studies involving 10292 individuals examining the association between aspirin and ARMD met the inclusion criteria. Meta-analysis was carried out by Cochrane Collaboration Review Manager 5.2 software (Cochrane Collaboration, Copenhagen, Denmark). Results: The pooled odd ratios showed that Aspirin use was associated with early ARMD (pooled odds ratio 1.43, 95% CI 1.09-1.88). Conclusions: There is a small but statistically significant association between Aspirin use and early ARMD, which may warrant further investigation.

引用

页码：35 / 39

页数：5

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