Synthesis and structural conformation of N-substituted 1,4-dihyropyridine derivatives

被引:0
作者
Mahendra, M
Doreswamy, BH
Sridhar, MA
Prasad, JS
Parecha, AR [1 ]
Patel, JA
Manvar, D
Dholaria, K
Shah, A
机构
[1] Univ Mysore, Dept Studies Phys, Mysore 570006, Karnataka, India
[2] Saurashtra Univ, Dept Chem, Rajkot 360005, Gujarat, India
关键词
N-substituted 1,4-dihyropyridine; synthesis; crystal structure;
D O I
10.1002/crat.200310539
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
N-(Phenyl)-3,5-dicarbethoxy-2,6-dimethyl-4-(phenyl)-1,4-dihydropyridine (A) and N-(4-methoxy phenyl)3,5 dicarbethoxy-2,6 dimethyl-4-(3-nitro phenyl)-1,4-dihydropyridine (13) has been synthesized as per scheme and characterized by the X-ray diffraction method. The compound A crystallizes in monoclinic space group P2(1)/c with cell parameters a = 9.2770(11)angstrom, b = 8.6410(5)angstrom, c = 27.601(3)angstrom, beta = 97.724(3)degrees, Z = 4. The compound B crystallizes in monoclinic space group P2(1)/c with cell parameters a = 11.229(6), b = 12.746(7)angstrom, c = 17.606(6)angstrom, beta = 104.531(3)degrees, Z = 4. The structures exhibit both intra and intermolecular hydrogen bonds. Dihydropyridine ring of both the compounds adopt a flat boat conformation.
引用
收藏
页码:92 / 97
页数:6
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