Brain-Derived Neurotrophic Factor Val66Met Polymorphism and Antidepressant Efficacy of Ketamine in Depressed Patients

被引:154
作者
Laje, Gonzalo [2 ]
Lally, Niall [3 ]
Mathews, Daniel [1 ]
Brutsche, Nancy [1 ]
Chemerinski, Anat [2 ]
Akula, Nirmala [2 ]
Kelmendi, Benjamin [4 ]
Simen, Arthur [4 ]
McMahon, Francis J. [2 ]
Sanacora, Gerard [4 ]
Zarate, Carlos, Jr. [1 ]
机构
[1] NIMH, Expt Therapeut & Pathophysiol Branch, Div Intramural Res Programs, NIH, Bethesda, MD 20892 USA
[2] NIMH, Human Genet Branch, Div Intramural Res Programs, NIH, Bethesda, MD 20892 USA
[3] UCL, Inst Cognit Neurosci, London, England
[4] Yale Univ, Sch Med, Dept Psychiat, New Haven, CT USA
关键词
D-ASPARTATE ANTAGONIST; MESSENGER-RNA; BDNF; TRIAL;
D O I
10.1016/j.biopsych.2012.05.031
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
引用
收藏
页码:E27 / E28
页数:2
相关论文
共 15 条
[1]   NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses [J].
Autry, Anita E. ;
Adachi, Megunai ;
Nosyreva, Elena ;
Na, Elisa S. ;
Los, Maarten F. ;
Cheng, Peng-fei ;
Kavalali, Ege T. ;
Monteggia, Lisa M. .
NATURE, 2011, 475 (7354) :91-U109
[2]   A Randomized Add-on Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Bipolar Depression [J].
Diazgranados, Nancy ;
Ibrahim, Lobna ;
Brutsche, Nancy E. ;
Newberg, Andrew ;
Kronstein, Phillip ;
Khalife, Sami ;
Kammerer, William A. ;
Quezado, Zenaide ;
Luckenbaugh, David A. ;
Salvadore, Giacomo ;
Machado-Vieira, Rodrigo ;
Manji, Husseini K. ;
Zarate, Carlos A., Jr. .
ARCHIVES OF GENERAL PSYCHIATRY, 2010, 67 (08) :793-802
[3]   Brain-derived neurotrophic factor (BDNF) gene: no major impact on antidepressant treatment response [J].
Domschke, Katharina ;
Lawford, Bruce ;
Laje, Gonzalo ;
Berger, Klaus ;
Young, Ross ;
Morris, Phillip ;
Deckert, Juergen ;
Arolt, Volker ;
McMahon, Francis J. ;
Baune, Bernhard T. .
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2010, 13 (01) :93-101
[4]   Voluntary exercise induces a BDNF-mediated mechanism that promotes neuroplasticity [J].
Gomez-Pinilla, F ;
Ying, Z ;
Roy, RR ;
Molteni, R ;
Edgerton, VR .
JOURNAL OF NEUROPHYSIOLOGY, 2002, 88 (05) :2187-2195
[5]   A RATING SCALE FOR DEPRESSION [J].
HAMILTON, M .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1960, 23 (01) :56-62
[6]   Course of Improvement in Depressive Symptoms to a Single Intravenous Infusion of Ketamine vs Add-on Riluzole: Results from a 4-Week, Double-Blind, Placebo-Controlled Study [J].
Ibrahim, Lobna ;
DiazGranados, Nancy ;
Franco-Chaves, Jose ;
Brutsche, Nancy ;
Henter, Ioline D. ;
Kronstein, Phillip ;
Moaddel, Ruin ;
Wainer, Irving ;
Luckenbaugh, David A. ;
Manji, Husseini K. ;
Zarate, Carlos A., Jr. .
NEUROPSYCHOPHARMACOLOGY, 2012, 37 (06) :1526-1533
[7]   mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists [J].
Li, Nanxin ;
Lee, Boyoung ;
Liu, Rong-Jian ;
Banasr, Mounira ;
Dwyer, Jason M. ;
Iwata, Masaaki ;
Li, Xiao-Yuan ;
Aghajanian, George ;
Duman, Ronald S. .
SCIENCE, 2010, 329 (5994) :959-964
[8]   Brain-Derived Neurotrophic Factor Val66Met Allele Impairs Basal and Ketamine-Stimulated Synaptogenesis in Prefrontal Cortex [J].
Liu, Rong-Jian ;
Lee, Francis S. ;
Li, Xiao-Yuan ;
Bambico, Francis ;
Duman, Ronald S. ;
Aghajanian, George K. .
BIOLOGICAL PSYCHIATRY, 2012, 71 (11) :996-1005
[9]   New insights into BDNF function in depression and anxiety [J].
Martinowich, Keri ;
Manji, Husseini ;
Lu, Bai .
NATURE NEUROSCIENCE, 2007, 10 (09) :1089-1093
[10]   Long-term repetitive transcranial magnetic stimulation increases the expression of brain-derived neurotrophic factor and cholecystokinin mRNA, but not neuropeptide tyrosine mRNA in specific areas of rat brain [J].
Müller, MB ;
Toschi, N ;
Kresse, AE ;
Post, A ;
Keck, ME .
NEUROPSYCHOPHARMACOLOGY, 2000, 23 (02) :205-215