Total synthesis of the marine pyrroloiminoquinone alkaloid tsitsikammamine A

被引：21

作者：

Rives, Arnaud ^{[1
]}

Delaine, Tamara ^{[1
]}

Legentil, Laurent ^{[1
]}

Delfourne, Evelyne ^{[1
]}

机构：

[1] Univ Toulouse 3, CNRS, UMR 5068, Lab Synth & Physicochim Mol Interet Biol, F-31062 Toulouse 9, France

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 10期

关键词：

Synthesis; Marine alkaloid; Pyrroloiminoquinone; Tsitsikammamine; PYRROLOQUINOLINE ALKALOIDS; BIOLOGICAL EVALUATION; NATURAL-PRODUCTS; ANALOGS; WAKAYIN; MAKALUVAMINES; INHIBITION; SPONGES;

D O I：

10.1016/j.tetlet.2008.12.078

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A concise route to the marine pyrroloiminoquinone alkaloid tsitsikammamine A and a regioisomer was developed. The synthesis was based on a Michael reaction between the indole dione 6 and 2'-amino-1-(4-methoxyphenyl)ethanol. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：1128 / 1130

页数：3