Total synthesis of the marine pyrroloiminoquinone alkaloid tsitsikammamine A

被引：21
作者：
Rives, Arnaud [1 ]
Delaine, Tamara [1 ]
Legentil, Laurent [1 ]
Delfourne, Evelyne [1 ]
机构：
[1] Univ Toulouse 3, CNRS, UMR 5068, Lab Synth & Physicochim Mol Interet Biol, F-31062 Toulouse 9, France
来源：
TETRAHEDRON LETTERS | 2009年 / 50卷 / 10期
关键词：
Synthesis; Marine alkaloid; Pyrroloiminoquinone; Tsitsikammamine; PYRROLOQUINOLINE ALKALOIDS; BIOLOGICAL EVALUATION; NATURAL-PRODUCTS; ANALOGS; WAKAYIN; MAKALUVAMINES; INHIBITION; SPONGES;
D O I：
10.1016/j.tetlet.2008.12.078
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A concise route to the marine pyrroloiminoquinone alkaloid tsitsikammamine A and a regioisomer was developed. The synthesis was based on a Michael reaction between the indole dione 6 and 2'-amino-1-(4-methoxyphenyl)ethanol. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1128 / 1130
页数：3
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