Dual thermo- and photo-responsive micelles based on miktoarm star polymers

被引：56
作者：
Blasco, Eva [1 ]
Schmidt, Bernhard V. K. J. [2 ,3 ]
Barner-Kowollik, Christopher [2 ,3 ]
Pinol, Milagros [1 ]
Oriol, Luis [1 ]
机构：
[1] Univ Zaragoza, Fac Ciencias, ICMA, CSIC,Dept Quim Organ, E-50009 Zaragoza, Spain
[2] Karlsruhe Inst Technol, Inst Tech Chem & Polymerchem, D-76128 Karlsruhe, Germany
[3] Karlsruhe Inst Technol, Inst Biol Grenzflachen, D-76344 Eggenstein Leopoldshafen, Germany
来源：
POLYMER CHEMISTRY | 2013年 / 4卷 / 16期
关键词：
BLOCK-COPOLYMER MICELLES; CLICK CHEMISTRY; AZOBENZENE; LIGHT; VESICLES; RELEASE;
D O I：
10.1039/c3py00576c
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
We report the synthesis and characterization of three novel azobenzene-containing miktoarm star polymers AB(3) (M-n = 14 800, D-M = 1.22, M-n = 17 400, D-M = 1.10 and M-n = 26 200, D-M = 1.12) as well as their self-assembly properties in water. The three polymers are composed of an azopolymer and three identical arms of poly(N,N-diethylacrylamide) (PDEAA), featuring thermo-responsive properties. By carefully selecting the polymerization degree of PDEAA, and consequently the hydrophobic/hydrophilic ratio, a specific miktoarm polymer has been identified that forms stable micelles in water as is clearly revealed by Transmission Electron Microscopy (TEM). In addition, the thermo-and photo-responsive properties of the polymeric micelles in water were investigated. Encapsulation of Nile Red was probed via fluorescence spectroscopy as well as its release from the loaded probes triggered by UV irradiation, which causes a trans-to-cis isomerisation of the azobenzene moieties.
引用
收藏
页码：4506 / 4514
页数：9
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