Coding or Noncoding, the Converging Concepts of RNAs

被引：122

作者：

Li, Jing ^{[1
]}

Liu, Changning ^{[1
]}

机构：

[1] Chinese Acad Sci, CAS Key Lab Trop Plant Resource & Sustainable Use, Xishuangbanna Trop Bot Garden, Innovat Acad Seed Design, Kunming, Yunnan, Peoples R China

来源：

FRONTIERS IN GENETICS | 2019年 / 10卷

基金：

中国国家自然科学基金;

关键词：

messenger RNA; long noncoding RNA; coding potential; ribosome profiling; micropeptide; MESSENGER-RNA; CIRCULAR RNAS; PROTEOGENOMIC CHARACTERIZATION; INDEPENDENT FUNCTION; SECONDARY STRUCTURE; TUMOR SUPPRESSION; SMALL ORFS; 3' UTRS; TRANSLATION; EVOLUTION;

D O I：

10.3389/fgene.2019.00496

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Technological advances over the past decade have unraveled the remarkable complexity of RNA. The identification of small peptides encoded by long non-coding RNAs (lncRNAs) as well as regulatory functions mediated by non-coding regions of mRNAs have further complicated our understanding of the multifaceted functions of RNA. In this review, we summarize current evidence pointing to dual roles of RNA molecules defined by their coding and non-coding potentials. We also discuss how the emerging roles of RNA transform our understanding of gene expression and evolution.

引用

页数：10

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