'Best supportive care' has had its day

被引:21
作者
Cullen, Michael [1 ]
机构
[1] Univ Hosp Birmingham, Canc Ctr, Queen Elizabeth Hosp, Birmingham B15 2TH, W Midlands, England
关键词
D O I
10.1016/S1470-2045(00)00260-6
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The term 'best supportive care' has been used since 1988 to describe the control arm in trials evaluating chemotherapy in advanced cancers. There are problems with this term. First, it implies that we more strenuously optimise these components of care in trials than in routine oncology practise, when there is no evidence that we do. Secondly, the name implies that it is effective, when usually it is not. Finally, 'best' suggests that we have reached a clear landmark of progress in non-chemotherapeutic palliation, when clearly we have not. 'Best supportive care' is an unhelpful and misleading term which should be avoided. In future trials, it should be replaced by 'standard palliative care ' with the type and frequency of key palliative interventions documented
引用
收藏
页码:173 / 175
页数:3
相关论文
共 10 条
[1]   Gemcitabine plus best supportive care (BSC) vs BSC in inoperable non-small cell lung cancer - a randomized trial with quality of life as the primary outcome [J].
Anderson, H. ;
Hopwood, P. ;
Stephens, R. J. ;
Thatcher, N. ;
Cottier, B. ;
Nicholson, M. ;
Milroy, R. ;
Maughan, T. S. ;
Falk, S. J. ;
Bond, M. G. ;
Burt, P. A. ;
Connolly, C. K. ;
McIllmurray, M. B. ;
Carmichael, J. .
BRITISH JOURNAL OF CANCER, 2000, 83 (04) :447-453
[2]  
Billingham L, 2000, J CLIN ONCOL, V18, P1802
[3]  
Billingham LJ, 2000, LUNG CANCER, V29, P4
[4]   Multicentre randomised controlled trial of nursing intervention for breathlessness in patients with lung cancer [J].
Bredin, M ;
Corner, J ;
Krishnasamy, M ;
Plant, H ;
Bailey, C ;
A'Hern, R .
BMJ-BRITISH MEDICAL JOURNAL, 1999, 318 (7188) :901-904
[5]   NON SMALL CELL LUNG-CANCER (NSCLC) - A PROSPECTIVE RANDOMIZED TRIAL WITH ALTERNATING CHEMOTHERAPY CEP/MEC' VERSUS NO TREATMENT [J].
CELLERINO, R ;
TUMMARELLO, D ;
PORFIRI, E ;
GUIDI, F ;
ISIDORI, P ;
RASPUGLI, M ;
BISCOTTINI, B ;
FATATI, G .
EUROPEAN JOURNAL OF CANCER & CLINICAL ONCOLOGY, 1988, 24 (12) :1839-1843
[6]   A RANDOMIZED TRIAL OF ALTERNATING CHEMOTHERAPY VERSUS BEST SUPPORTIVE CARE IN ADVANCED NON-SMALL-CELL LUNG-CANCER [J].
CELLERINO, R ;
TUMMARELLO, D ;
GUIDI, F ;
ISIDORI, P ;
RASPUGLI, M ;
BISCOTTINI, B ;
FATATI, G .
JOURNAL OF CLINICAL ONCOLOGY, 1991, 9 (08) :1453-1461
[7]   Mitomycin, ifosfamide, and cisplatin in unresectable non-small-cell lung cancer: Effects on survival and quality of life [J].
Cullen, MH ;
Billingham, LJ ;
Woodroffe, CM ;
Chetiyawardana, AD ;
Gower, NH ;
Joshi, R ;
Ferry, DR ;
Rudd, RM ;
Spiro, SG ;
Cook, JE ;
Trask, C ;
Bessell, E ;
Connolly, CK ;
Tobias, J ;
Souhami, RL .
JOURNAL OF CLINICAL ONCOLOGY, 1999, 17 (10) :3188-3194
[8]   Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer [J].
Cunningham, D ;
Pyrhönen, S ;
James, RD ;
Punt, CJA ;
Hickish, TF ;
Heikkila, R ;
Johannesen, TB ;
Starkhammar, H ;
Topham, CA ;
Awad, L ;
Jacques, C ;
Herait, P .
LANCET, 1998, 352 (9138) :1413-1418
[9]   CHEMOTHERAPY CAN PROLONG SURVIVAL IN PATIENTS WITH ADVANCED NON-SMALL-CELL LUNG-CANCER - REPORT OF A CANADIAN MULTICENTER RANDOMIZED TRIAL [J].
RAPP, E ;
PATER, JL ;
WILLAN, A ;
CORMIER, Y ;
MURRAY, N ;
EVANS, WK ;
HODSON, DI ;
CLARK, DA ;
FELD, R ;
ARNOLD, AM ;
AYOUB, JI ;
WILSON, KS ;
LATREILLE, J ;
WIERZBICKI, RF ;
HILL, DP .
JOURNAL OF CLINICAL ONCOLOGY, 1988, 6 (04) :633-641
[10]   Prospective randomized trial of docetaxel versus best supportive care in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy [J].
Shepherd, FA ;
Dancey, J ;
Ramlau, R ;
Mattson, K ;
Gralla, R ;
O'Rourke, M ;
Levitan, N ;
Gressot, L ;
Vincent, M ;
Burkes, R ;
Coughlin, S ;
Kim, Y ;
Berille, J .
JOURNAL OF CLINICAL ONCOLOGY, 2000, 18 (10) :2095-2103