Direct Benzothiophene Formation via Oxygen-Triggered Intermolecular Cyclization of Thiophenols and Alkynes Assisted by Manganese/PhCOOH

被引：78

作者：

Liu, Kaisheng ^{[1
]}

Jia, Fan ^{[1
]}

Xi, Hui ^{[1
]}

Li, Yuanming ^{[1
]}

Zheng, Xiaojian ^{[1
]}

Quo, Qiaoxia ^{[2
]}

Shen, Baojian ^{[2
]}

Li, Zhiping ^{[1
,2
]}

机构：

[1] Renmin Univ China, Dept Chem, Beijing 100872, Peoples R China

[2] China Univ Petr, State Key Lab Heavy Oil Proc, Beijing 102249, Peoples R China

来源：

ORGANIC LETTERS | 2013年 / 15卷 / 08期

基金：

美国国家科学基金会;

关键词：

CATALYZED PROTODECARBOXYLATION; BOND FORMATION; C-S; INDOLES; DERIVATIVES; ANILINES; ROUTE; ARENE; BENZOFURANS; OXIDATION;

D O I：

10.1021/ol400719d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An intermolecular oxidative cyclization between thiophenols and alkynes for benzothiophene formation has been established. A variety of multifunctional benzothiophenes are synthesized. In addition, we demonstrated that the obtained benzothiophenes can be used for further transformation to give diverse benzothiophene derivatives efficiently and selectively.

引用

页码：2026 / 2029

页数：4

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