Modelling of icosahedral viruses

被引:14
作者
Angelescu, Daniel George [1 ,2 ]
Linse, Per [1 ]
机构
[1] Lund Univ, SE-22100 Lund, Sweden
[2] Romanian Acad, Inst Phys Chem IG Murgulescu, Bucharest 060021, Romania
关键词
Virus; Capsid; dsDNA; ssRNA; Modelling; Spool structure; Thermodynamics; Self-assembly;
D O I
10.1016/j.cocis.2007.10.004
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Theoretical and simulation investigations of viruses attaining icosahedral shape based on molecular models have recently become an exciting and rapidly growing research area. We discuss recent studies addressing the packing of the genome inside the capsid, thermodynamics, and the self-assembly of capsids. Special attention is given to the different packing of double-stranded and single-stranded polynucleotides in the viral capsid and its consequences. (C) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码:389 / 394
页数:6
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