Comparison of risk scoring systems in predicting clinical outcome at upper gastrointestinal bleeding patients in an emergency unit

被引:59
作者
Dicu, Daniela [1 ]
Pop, Felicia [2 ]
Ionescu, Daniela [3 ,4 ]
Dicu, Tiberius [5 ]
机构
[1] Reg Inst Gastroenterol & Hepatol O Fodor, Emergency Dept, Cluj Napoca, Romania
[2] Reg Inst Gastroenterol & Hepatol O Fodor, Transfus Dept, Cluj Napoca, Romania
[3] Iuliu Hatieganu Univ Med & Pharm, Dept Anesthesia & Intens Care 1, Cluj Napoca, Romania
[4] Outcome Res Consortium, Cleveland, OH USA
[5] Univ Babes Bolyai, Fac Environm Sci & Engn, R-3400 Cluj Napoca, Romania
关键词
ENDOSCOPIC THERAPY; ROCKALL SCORE; OUTPATIENT MANAGEMENT; HEMORRHAGE; ERYTHROMYCIN; BLATCHFORD; VALIDATION; NEED; INFUSION; TRIAL;
D O I
10.1016/j.ajem.2012.06.009
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Background: Admission Rockall score (RS), full RS, and Glasgow-Blatchford Bleeding Score (GBS) can all be used to stratify the risk in patients presenting with upper gastrointestinal bleeding (UGIB) in the emergency department (ED). The aim of our study was to compare both admission and full RS and GBS in predicting outcomes at UGIB patients in a Romanian ED. Patients and Methods: A total of 229 consecutive patients with UGIB were enrolled in the study. Patients were followed up 60 days after admission to ED because of UGIB episode to determine cases of rebleeding or death during this period. By using areas under the curve (AUCs), we compared the 3 scores in terms of identifying the most predictive score of unfavorable outcomes. Results: Rebleeding rate was 40.2% (92 patients), and mortality rate was 18.7% (43 patients). For the prediction of mortality, full RS was superior to GBS (AUC, 0.825 vs 0.723; P=.05) and similar to admission RS (AUC, 0.792). Glasgow-Blatchford Bleeding Score had the highest accuracy in detecting patients who needed transfusion (AUC, 0.888) and was superior to both the admission RS and full RS (AUC, 0.693 and 0.750, respectively) (P<.0001). In predicting the need for intervention, the GBS was superior to both the admission RS and full RS (AUC, 0.868, 0.674, and 0.785, respectively) (P<.0001 and P=.04, respectively). Conclusions: The GBS can be used to predict need for intervention and transfusion in patients with UGIB in our ED, whereas full RS can be successfully used to stratify the mortality risk in these patients. (C) 2013 Elsevier Inc. All rights reserved.
引用
收藏
页码:94 / 99
页数:6
相关论文
共 27 条
[1]   Meta-analysis: erythromycin before endoscopy for acute upper gastrointestinal bleeding [J].
Bai, Y. ;
Guo, J. -F. ;
Li, Z. -S. .
ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2011, 34 (02) :166-171
[2]   Applicability of the Rockall score in patients undergoing endoscopic therapy for upper gastrointestinal bleeding [J].
Bessa, X ;
O'Callaghan, E ;
Ballesté, B ;
Nieto, M ;
Seoane, A ;
Panadès, A ;
Vazquez, DJ ;
Andreu, M ;
Bory, E .
DIGESTIVE AND LIVER DISEASE, 2006, 38 (01) :12-17
[3]   A risk score to predict need for treatment for upper-gastrointestinal haemorrhage [J].
Blatchford, O ;
Murray, WR ;
Blatchford, M .
LANCET, 2000, 356 (9238) :1318-1321
[4]   Hospitalized incidence and case fatality for upper gastrointestinal bleeding from 1999 to 2007: a record linkage study [J].
Button, L. A. ;
Roberts, S. E. ;
Evans, P. A. ;
Goldacre, M. J. ;
Akbari, A. ;
Dsilva, R. ;
Macey, S. ;
Williams, J. G. .
ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2011, 33 (01) :64-76
[5]   Comparison of three different risk scoring systems in non-variceal upper gastrointestinal bleeding [J].
Camellini, L ;
Merighi, A ;
Pagnini, C ;
Azzolini, F ;
Guazzetti, S ;
Scarcelli, A ;
Manenti, F ;
Rigo, GP .
DIGESTIVE AND LIVER DISEASE, 2004, 36 (04) :271-277
[6]  
Chandra S, 2011, AM J EMERG MED
[7]  
Chen ZJ, 2011, WORLD J EMERG MED, V2, P5, DOI 10.5847/wjem.j.1920-8642.2011.01.001
[8]   Relevance of the Rockall score in patients undergoing endoscopic therapy for peptic ulcer haemorrhage [J].
Church, NI ;
Palmer, KR .
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 2001, 13 (10) :1149-1152
[9]   Erythromycin improves the quality of EGD in patients with acute upper GI bleeding:: a randomized controlled study [J].
Coffin, B ;
Pocard, M ;
Panis, Y ;
Riche, F ;
Lainé, MJ ;
Bitoun, A ;
Lémann, M ;
Bouhnik, Y ;
Valleur, P .
GASTROINTESTINAL ENDOSCOPY, 2002, 56 (02) :174-179
[10]   UPPER GASTROINTESTINAL-BLEEDING - NATURE AND MAGNITUDE OF THE PROBLEM IN THE UNITED-STATES [J].
CUTLER, JA ;
MENDELOFF, AI .
DIGESTIVE DISEASES AND SCIENCES, 1981, 26 (07) :S90-S96