Energy landscape and native-state structure of proteins - A simplified model

被引：30

作者：

Flammini, A

Banavar, JR

Maritan, A

机构：

[1] Scuola Int Super Studi Avanzati, Trieste, Italy

[2] INFM, Trieste, Italy

[3] Penn State Univ, Dept Phys, Davey Lab 104, University Pk, PA 16802 USA

来源：

EUROPHYSICS LETTERS | 2002年 / 58卷 / 04期

关键词：

D O I：

10.1209/epl/i2002-00441-9

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We present a theoretical framework for the study of the protein folding problem and apply it to the helix, a beta-hairpin structure and to one globular protein. The knowledge of the native-state structure of a protein can be used to deduce the free-energy landscape and to probe the dynamical behavior of proteins.

引用

收藏

页码：623 / 629

页数：7

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